原理
淀粉样蛋白是以刚果红（一种异染性染料）在组织中检测。以碱性氯化钠预处理组织可以强化染色效果。
仅试剂盒组分
产品编号
说明
- Congo Red Solution (kit only) 500 mL
- Sodium Chloride Solution, Alcoholic (kit only) 500 mL
- Sodium Hydroxide Solution (kit only) 2 x 12
相关产品
产品编号
说明
价格
警示用语：
Danger
危险分类
Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - Met. Corr. 1 - Skin Irrit. 2
储存分类代码
3 - Flammable liquids
闪点(°F)
57.2 °F - closed cup
闪点(°C)
14.0 °C - closed cup
法规信息
监管及禁止进口产品
Laurence Ozmen et al.
Neuro-degenerative diseases, 2(6), 284-298 (2006-08-16)
Most of the transgenic mice generated to model Alzheimer's disease express human amyloid precursor protein (APP) mutants alone or in conjunction with presenilin mutants. We have generated a mouse model by overexpressing human BACE and human APP with the V717F
J Grayson Richards et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 23(26), 8989-9003 (2003-10-03)
Transgenic mice, expressing mutant beta-amyloid precursor proteins (betaAPPs), have lead to a better understanding of the pathophysiological processes in Alzheimer's disease (AD). In many of these models, however, the temporal development of cognitive decline and the relationship to Abeta deposition
Samir K Maji et al.
PLoS biology, 6(2), e17-e17 (2008-02-08)
Amyloids are highly organized protein aggregates that are associated with both neurodegenerative diseases such as Alzheimer disease and benign functions like skin pigmentation. Amyloids self-polymerize in a nucleation-dependent manner by recruiting their soluble protein/peptide counterpart and are stable against harsh
Antje Willuweit et al.
Frontiers in neuroscience, 15, 699926-699926 (2021-10-22)
Alzheimer's disease (AD) is characterized by formation of amyloid plaques and neurofibrillary tangles in the brain, which can be mimicked by transgenic mouse models. Here, we report on the characterization of amyloid load in the brains of two transgenic amyloidosis
Lei Wang et al.
PLoS biology, 6(8), e195-e195 (2008-08-08)
Protein aggregation is a process in which identical proteins self-associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as amorphous, lacking any long-range order, or highly ordered fibrils. Protein fibrils can be composed of native globular molecules, such
实验方案
A stem cell culture protocol to generate 3D NSC models of Alzheimer’s disease using ReNcell human neural stem cell lines.
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