H6886
S -己基谷胱甘肽
>98% (TLC), suitable for ligand binding assays
别名:
还原型 S-己基-L-谷胱甘肽
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关于此项目
经验公式（希尔记法）:
C16H29N3O6S
化学文摘社编号:
分子量:
391.48
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
5629635
产品名称
S -己基谷胱甘肽,
InChI
1S/C16H29N3O6S/c1-2-3-4-5-8-26-10-12(15(23)18-9-14(21)22)19-13(20)7-6-11(17)16(24)25/h11-12H,2-10,17H2,1H3,(H,18,23)(H,19,20)(H,21,22)(H,24,25)/t11-,12-/m0/s1
SMILES string
CCCCCCSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
InChI key
HXJDWCWJDCOHDG-RYUDHWBXSA-N
assay
>98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
mp
200-202 °C
storage temp.
2-8°C
Quality Level
Application
用于谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱法的配体。
Biochem/physiol Actions
S-己基谷胱甘肽可用作谷胱甘肽-S-转移酶和谷胱甘肽过氧化物酶的亲和色谱配体。S-己基谷胱甘肽也用作抑制剂，研究酶的特异性和动力学，如线粒体膜结合谷胱甘肽转移酶 (mtMGST1)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Liqing Chen et al.
Acta crystallographica. Section D, Biological crystallography, 59(Pt 12), 2211-2217 (2003-12-04)
Glutathione S-transferases (GSTs) are a major family of detoxification enzymes which possess a wide range of substrate specificities. Most organisms possess many GSTs belonging to multiple classes. Interest in GSTs in insects is focused on their role in insecticide resistance;
Markus Perbandt et al.
The Journal of biological chemistry, 280(13), 12630-12636 (2005-01-11)
Onchocerciasis is a debilitating parasitic disease caused by the filarial worm Onchocerca volvulus. Similar to other helminth parasites, O. volvulus is capable of evading the host's immune responses by a variety of defense mechanisms, including the detoxification activities of the
Y Hathout et al.
Chemical research in toxicology, 9(6), 1044-1049 (1996-09-01)
Interaction of chlorambucil and the glutathione-depleted human placenta pi class glutathione S-transferase (pi GST) results in the formation of a complex between the drug and the protein at physiological pH. This complex is not formed in the presence of glutathione
Natalya Kurochkina et al.
Journal of theoretical biology, 283(1), 92-102 (2011-05-31)
Helix-helix parallel interfaces can be characterized by certain combinations of amino acids, which repeatedly occur at core positions a and d (leucine zipper nomenclature) in homologous and nonhomologous proteins and influence interhelical angles. Applied for the prediction of interhelical angles
M Bäck et al.
British journal of pharmacology, 133(7), 1134-1144 (2001-08-07)
Contractions of guinea-pig tracheal preparations to cysteinyl-leukotrienes (LTC(4), LTD(4) and LTE(4)) were characterized in organ baths, and cysteinyl-leukotriene metabolism was studied using radiolabelled agonists and RP-HPLC separation. In the presence of S-hexyl GSH (100 microM) the metabolism of [(3)H]-LTC(4) into
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