H6515
L -高丝氨酸
别名:
( S )-2-氨基-4-羟基丁酸, Hse
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关于此项目
线性分子式:
HOCH2CH2CH(NH2)CO2H
化学文摘社编号:
分子量:
119.12
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
211-590-6
MDL number:
Beilstein/REAXYS Number:
1721681
SMILES string
N[C@@H](CCO)C(O)=O
InChI
1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChI key
UKAUYVFTDYCKQA-VKHMYHEASA-N
assay
≥98% (TLC)
form
powder
color
white to off-white
mp
203 °C (dec.) (lit.)
application(s)
cell analysis
detection
Quality Level
General description
L-高丝氨酸是丝氨酸的变体，其侧链上多了一个碳。
Application
L-高丝氨酸用作神经递质分析和氨基酸量化的内标物。
Biochem/physiol Actions
L -高丝氨酸由高丝氨酸脱氢酶催化氧化过程而合成。这是合成L-苏氨酸的步骤之一。这一反应维持了大肠肝菌等细菌中的碳通量。
L-高丝氨酸用于蛋氨酸、苏氨酸和异亮氨酸的生物合成。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Neurotoxic effect of maneb in rats as studied by neurochemical and immunohistochemical parameters
Nielsen BS, et al.
Environmental Toxicology and Pharmacology, 21(3), 268-275 (2006)
Reprogramming Microbial Metabolic Pathways, 288-288 (2012)
Chiral recognition of non-natural ?-amino acids
Gal JF, et al.
International Journal of Mass Spectrometry, 222(1?3), 259-267 (2003)
Quantification of 3-deoxyglucosone (3DG) as an aging marker in natural and forced aged wines
Oliveira CM, et al.
J. Food Compos. Anal., 70?76-70?76 (2016)
D C Turnell et al.
Clinical chemistry, 28(3), 527-531 (1982-03-01)
This method for estimating clinically important amino acids in serum or urine within 40 min involves o-phthalaldehyde/2-mercaptoethanol derivatization and reversed-phase "high-pressure" liquid chromatography. Homocysteic acid is an internal standard, and homoserine and norvaline are reference peaks. For all the amino
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