product name
L-组氨酸 单盐酸盐 一水合物, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-101.0%
生物来源
non-animal source
质量水平
Agency
meets EP testing specifications
产品线
BioXtra
检测方案
98.5-101.0%
形式
crystalline powder
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
white
mp
254 °C (dec.) (lit.)
溶解性
H2O: 100 mg/mL
SMILES字符串
O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O
InChI
1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1
InChI key
CMXXUDSWGMGYLZ-XRIGFGBMSA-N
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应用
L-组氨酸盐酸盐水合物已可用于蜜蜂细胞培养基中。
非动物源性L-组氨酸盐酸盐被用于生物制造用细胞培养基配方中。 使用非动物来源的L-组氨酸和其他成分可避免外来病毒污染生物制品的风险。
生化/生理作用
L-组氨酸参与一碳单位代谢。它与蛋白质甲基化有关。L-组氨酸是血红蛋白结构和功能的一部分。L-组氨酸是具有抗氧化性的二肽的组分。组氨酸是组胺形成的前体，与过敏反应有关。尿酸是皮肤的免疫反应调节剂，它也是由组氨酸生物合成的。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Carlota Diaz Sanchez-Bustamante et al.
Biotechnology and bioengineering, 93(1), 169-180 (2005-10-29)
A precise understanding of processes managing heterologous protein production in vitro and in vivo is essential for the manufacture of sophisticated biopharmaceuticals as well as for future gene therapy and tissue engineering initiatives. Capitalizing on the gravity-enforced self-assembly of monodispersed
Jean-Christophe Drugmand et al.
Biotechnology advances, 30(5), 1140-1157 (2011-10-11)
Insect cells (IC) and particularly lepidopteran cells are an attractive alternative to mammalian cells for biomanufacturing. Insect cell culture, coupled with the lytic expression capacity of baculovirus expression vector systems (BEVS), constitutes a powerful platform, IC-BEVS, for the abundant and
Yoshihiro Kaneko et al.
Journal of bioscience and bioengineering, 109(3), 274-280 (2010-02-18)
Pharmaceutical manufacturing plants can be operated continuously for several months. It is therefore important to use cells with long-term stability for the production of active ingredients. We investigated the reliability and long-term stability of an antibody-producing cell line. A recombinant
D J Williams et al.
IEE proceedings. Nanobiotechnology, 152(6), 207-210 (2006-01-31)
Tissue engineering and regenerative medicine are interdisciplinary fields that apply principles of engineering and life sciences to develop biological substitutes, typically composed of biological and synthetic components, that restore, maintain or improve tissue function. Many tissue engineering technologies are still
Medium for development of bee cell cultures (Apis mellifera: Hymenoptera: Apidae).
Hunter WB
In Vitro Cellular & Developmental Biology. Animal, 46(2), 83-86 (2010)
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