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Merck
CN

H5134

Sigma-Aldrich

D-Homocystine

≥98% (TLC)

别名:

(R,R)-4,4′-Dithiobis(2-aminobutanoic acid)

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About This Item

经验公式(希尔记法):
C8H16N2O4S2
CAS号:
分子量:
268.35
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

D-Homocystine,

方案

≥98% (TLC)

质量水平

表单

powder

颜色

white to off-white

SMILES字符串

N[C@H](CCSSCC[C@@H](N)C(O)=O)C(O)=O

InChI

1S/C8H16N2O4S2/c9-5(7(11)12)1-3-15-16-4-2-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6-/m1/s1

InChI key

ZTVZLYBCZNMWCF-PHDIDXHHSA-N

生化/生理作用

D-Homocystine may be used in the preparation of carbocyclic nucleoside such as S-aristeromycinyl-L-homocysteine for use in studied on S-adenosylmethionine-dependent methyltransferase inhibitors.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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D M Houston et al.
Journal of medicinal chemistry, 28(4), 478-482 (1985-04-01)
A series of base- and amino acid modified analogues of S-aristeromycinyl-L-homocysteine, a carbocyclic nucleoside, were synthesized and evaluated as inhibitors of S-adenosyl-L-methionine-dependent methyltransferases, including catechol O-methyltransferase, phenylethanolamine N-methyltransferase, and histamine N-methyltransferase. The base-modified analogues (8-azaadenine, 3-deazaadenine, and N6-methyladenine) were prepared
S-Aristeromycinyl-L-homocysteine, a potent inhibitor of S-adenosylmethionine-dependent transmethylations.
R T Borchardt et al.
Journal of medicinal chemistry, 19(1), 197-198 (1976-01-01)

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