H1650
抗HLA I类抗原单克隆抗体 小鼠抗
clone W6/32, purified immunoglobulin, buffered aqueous solution
别名:
抗HLA I类抗原单克隆抗体
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
W6/32, monoclonal
Application:
flow cytometry
immunoprecipitation (IP)
indirect immunofluorescence
immunoprecipitation (IP)
indirect immunofluorescence
Species reactivity:
monkey, human
Citations:
43
Technique(s):
flow cytometry: 5 μL using 1 × 106 cells
immunoprecipitation (IP): suitable
indirect immunofluorescence: 1:10 using acetone-fixed human tonsil frozen sections.
immunoprecipitation (IP): suitable
indirect immunofluorescence: 1:10 using acetone-fixed human tonsil frozen sections.
Uniprot accession no.:
产品名称
抗HLA I类抗原单克隆抗体 小鼠抗, clone W6/32, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
W6/32, monoclonal
form
buffered aqueous solution
species reactivity
monkey, human
technique(s)
flow cytometry: 5 μL using 1 × 106 cells
immunoprecipitation (IP): suitable
indirect immunofluorescence: 1:10 using acetone-fixed human tonsil frozen sections.
isotype
IgG2a
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HLA-A(3105), HLA-B(3106), HLA-C(3107)
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Application
成功使用该抗体的应用以及相关的同行评审论文如下所示。
免疫荧光分析（1篇论文）
免疫荧光分析（1篇论文）
Biochem/physiol Actions
HLA-A、HLA-B和HLA−C等HLA I类分子将内源性抗原呈递给CD8+（分化簇8）T细胞。
识别大多数人类有核细胞上表达的人类HLA I类抗原。抗体与人I类HLA分子(HLA-A,B,C)的44-45 kDa α-链多肽上的单态表位反应。该抗体可用于丙酮固定的冰冻切片和细胞涂片的免疫沉淀、补体介导细胞毒性分析、流式细胞分析和免疫组化染色。其可与非洲和亚洲猿猴以及旧大陆猴的细胞发生交叉反应。其与大多数新大陆猴或非灵长类动物的细胞均未见反应性。该抗体识别的表位对常规福尔马林固定和石蜡包埋敏感。
第 4 次研讨会：代码P1
第 5 次研讨会：代码 BP166、BP288、BP407、B 005
第 4 次研讨会：代码P1
第 5 次研讨会：代码 BP166、BP288、BP407、B 005
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途，或人类或动物任何类型的消费或使用。
General description
I类蛋白质具有高度多态性，其中HLA-B几乎是人类基因组中多态性最高的基因。HLA-A、HLA-B、HLA-C是经典的I类蛋白和异二聚体。HLA-A、HLA-B、HLA-C由多态性跨膜α重链和不变的水溶性轻链组成。HLA-B 位于人染色体 6p21上。
以前分配的蛋白质标识符P01891 已经合并为P04439。完整的详细资料见于UniProt数据库。
以前分配的蛋白质标识符P01891 已经合并为P04439。完整的详细资料见于UniProt数据库。
Immunogen
人扁桃体白细胞膜制备。
Physical form
溶于0.01M磷酸盐缓冲盐水，pH 7.4，含有1%牛血清白蛋白以及15 mM叠氮化钠
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
常规特殊物品
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Datasheet
Datasheet
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