G7251
甘氨酸酐
≥99% (TLC)
别名:
2,5-二酮哌嗪, 2,5-哌嗪二酮
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选择尺寸
关于此项目
经验公式（希尔记法）:
C4H6N2O2
化学文摘社编号:
分子量:
114.10
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
203-411-5
MDL number:
Beilstein/REAXYS Number:
112112
产品名称
甘氨酸酐, cyclic dipeptide
InChI
1S/C4H6N2O2/c7-3-1-5-4(8)2-6-3/h1-2H2,(H,5,8)(H,6,7)
InChI key
BXRNXXXXHLBUKK-UHFFFAOYSA-N
SMILES string
O=C1CNC(=O)CN1
assay
≥99% (TLC)
form
powder
color
white
mp
>300 °C (lit.)
Quality Level
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Application
- 光诱导氢原子提取法氧化环状二肽的研究。激光闪光FT EPR和光谱学研究。该研究考察了环状二肽的氧化工艺，重点研究了甘氨酸酐在光诱导氢原子提取反应中的作用（Tarábek et al., 2007）。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
R Shukla et al.
Peptides, 15(8), 1471-1474 (1994-01-01)
Central administration of exogenous cyclo(His-Pro) (CHP) is known to produce hypothermia in rodents. In the present study, we examined the role of endogenous CHP in cold-induced hypothermia in the desert rat, Mastomys natalensis. The results of these studies show that
Liyun Zhang et al.
Amino acids, 43(1), 279-287 (2011-09-16)
Cyclic dipeptides, due to their chemical properties and various bioactivities, are very attractive for medicinal chemistry. Fragmentations of three simple cyclic dipeptides including cyclo(Gly-Gly), cyclo(Ala-Ala) and cyclo(Gly-Val) in the gas-phase are determined with synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry
A K Szardenings et al.
Journal of medicinal chemistry, 41(13), 2194-2200 (1998-06-19)
The discovery of a novel series of heterocyclic matrix metalloproteinase (MMPs) inhibitors is described. Published crystal structures of peptidyl hydroxamates bound to MMPs were the basis for the rational design of diketopiperazine (DKP) inhibitors. Combinatorial libraries were prepared and evaluated
J Haginaka et al.
The Journal of pharmacy and pharmacology, 38(3), 225-226 (1986-03-01)
A sensitive, high-performance liquid chromatographic method has been developed for the determination of piperazine-2,5-dione, a new metabolite of ampicillin, in human urine. Piperazine-2,5-dione was separated from human urine on a C18-column using phosphate buffer-methanol (pH 3.5) as eluent. Subsequently, the
M Prudel et al.
Die Nahrung, 29(4), 381-389 (1985-01-01)
A HPLC method for the determination of Usal (Aspartame hydrochloride, L-aspartyl-L-phenylalanine methyl ester hydrochloride) and its decomposition products was elaborated. Aspartic acid, phenylalanine, phenylalanine methyl ester, aspartyl-phenylalanine, phenylalanyl-aspartic acid, 5-benzyl-3,6-dioxo-2-piperazineacetic acid (DOP) and Usal were separated on Separon SI C-18.
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