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Merck
CN
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文件

G7127

Sigma-Aldrich

鸟苷 5'-二磷酸 钠盐

Type I, ≥96% (HPLC)

别名:

GDP

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About This Item

经验公式（希尔记法）:
C10H15N5O11P2
CAS号:
43139-22-6
分子量:
443.20
MDL编号:
MFCD00070121
UNSPSC代码:
41106305
PubChem化学物质编号:
24895291
NACRES:
NA.51

生物来源

synthetic (organic)

质量水平

300

类型

Type I

检测方案

≥96% (HPLC)

形式

powder

运输

dry ice

储存温度

−20°C

SMILES字符串

[Na].NC1=NC(=O)c2ncn(C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O)c2N1

InChI

1S/C10H15N5O11P2.Na.H/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18);;

InChI key

PVMPTWQLNDHIEV-UHFFFAOYSA-N

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相关类别

应用

鸟苷 5′-二磷酸钠盐用于：
  • GTP-γ-35S官能化分析
  • Y1激动剂激活[35S]-鸟苷5′-O-(3-硫醇）三磷酸 (GTPγS)官能化结合
  • 重组蛋白表达和纯化

生化/生理作用

鸟苷5′-二磷酸 (GDP)是嘌呤鸟嘌呤的二磷酸核苷。GDP和GTP参与并且用于通过G-偶联蛋白受体（GCPR）和鸟嘌呤核苷酸交换因子（GEF）以及多种GTP酶作用的细胞信号研究。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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实验方案

HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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