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G7127

鸟苷 5'-二磷酸钠盐

Name: 鸟苷 5'-二磷酸 钠盐
Brand: SIGMA
Price: 742.44 CNY
Availability: InStock

Type I, ≥96% (HPLC)

别名:

GDP

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50 MG

¥742.44

250 MG

¥1,298.61

1 G

¥3,898.56

¥742.44

国内现货，预计发货时间2025年4月24日详情

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50 MG

¥742.44

250 MG

¥1,298.61

1 G

¥3,898.56

About This Item

经验公式（希尔记法）:

C₁₀H₁₅N₅O₁₁P₂

CAS号:

43139-22-6

分子量:

443.20

MDL编号:

MFCD00070121

UNSPSC代码:

41106305

PubChem化学物质编号:

24895291

NACRES:

NA.51

¥742.44

国内现货，预计发货时间2025年4月24日详情

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此商品	B5002	B0631	I7125
B9285 5-溴-2′-脱氧尿苷	B5002 5-溴-2′-脱氧尿苷	B0631 5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt	I7125 5-碘-2′-脱氧尿苷
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
assay ≥99%	assay ≥99% (HPLC)	assay ≥90%	assay ≥99% (HPLC)
form powder	form powder	form powder	form powder or crystals
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. 2-8°C
solubility NH₄OH: 0.1 M at 20 °C, clear, colorless	solubility DMSO: 50 mg/mL, clear, colorless to very faintly yellow	solubility water: 50 mg/mL, clear, colorless to faintly yellow	solubility 1 N NH₄OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow

应用

鸟苷 5′-二磷酸钠盐用于：

GTP-γ-35S官能化分析[1]
Y1激动剂激活[35S]-鸟苷5′-O-(3-硫醇）三磷酸 (GTPγS)官能化结合[2]
重组蛋白表达和纯化[3]

生化/生理作用

鸟苷5′-二磷酸 (GDP)是嘌呤鸟嘌呤的二磷酸核苷。GDP和GTP参与并且用于通过G-偶联蛋白受体（GCPR）和鸟嘌呤核苷酸交换因子（GEF）以及多种GTP酶作用的细胞信号研究。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

技术规格说明书

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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N-desalkylquetiapine, a potent norepinephrine reuptake inhibitor and partial 5-HT 1A agonist, as a putative mediator of quetiapine's antidepressant activity

Jensen N H, et al.

Neuropsychopharmacology, 33(10), 2303-2303 (2008)

A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease

Yanagisawa M, et al.

The Journal of Biological Chemistry, 283(26), 18344-18354 (2008)

Effect of in vivo exposure to ambient fine particles (PM2.5) on the density of dopamine D2-like receptors and dopamine-induced [35S]-GTPγS binding in rat prefrontal cortex and striatum membranes.

María-de-Los-Angeles Andrade-Oliva et al.

Environmental toxicology and pharmacology, 60, 58-65 (2018-04-17)

Male Sprague-Dawley rats (8-9 weeks-old) were exposed for three days (acute exposure) or eight weeks (subchronic exposure) to purified air or concentrated ambient fine particles, PM2.5 (≤2.5 μm; 15 to 18-fold of ambient air; 370-445 μg/m3). In membranes from rat prefrontal cortex

Neuropeptide Y promotes neurogenesis in murine subventricular zone

Agasse F, et al.

Stem Cells, 26(6), 1636-1645 (2008)

The eubacterial protein synthesis inhibitor pulvomycin interacts with archaeal elongation factor 1α from Sulfolobus solfataricus.

Nicola M Martucci et al.

Biochimie, 94(2), 503-509 (2011-09-20)

The effect of pulvomycin on the biochemical and fluorescence spectroscopic properties of the archaeal elongation factor 1α from Sulfolobus solfataricus (SsEF-1α), the functional analog of eubacterial EF-Tu, was investigated. The antibiotic was able to reduce in vitro the rate of protein

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实验方案

HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

LC/MS Analysis of Nucleotides SeQuant^® ZIC^®-cHILIC – Effect of pH

ZIC^®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

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鸟苷 5'-二磷酸钠盐

Type I, ≥96% (HPLC)

选择尺寸