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Merck
CN

G3882

Sigma-Aldrich

Gly-Gly-Gly-Gly

≥98% (TLC)

别名:

Glycyl-glycyl-glycyl-glycine, Tetraglycine, Triglycyl-glycine

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About This Item

线性分子式:
NH2CH2CO(NHCH2CO)3OH
CAS号:
分子量:
246.22
Beilstein:
1715387
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

Gly-Gly-Gly-Gly,

方案

≥98% (TLC)

质量水平

表单

powder

颜色

white to off-white

mp

300 °C

应用

peptide synthesis

储存温度

−20°C

SMILES字符串

NCC(=O)NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C8H14N4O5/c9-1-5(13)10-2-6(14)11-3-7(15)12-4-8(16)17/h1-4,9H2,(H,10,13)(H,11,14)(H,12,15)(H,16,17)

InChI key

QMOQBVOBWVNSNO-UHFFFAOYSA-N

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Amino Acid Sequence

Gly-Gly-Gly-Gly

生化/生理作用

Tetraglycine is used with copper (Cu-II) to study mechanisms of hydrogen peroxide/bicarbonate free radical production and effect in vitro.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fabian Barthels et al.
ChemMedChem, 15(10), 839-850 (2020-03-03)
Staphylococcus aureus is one of the most frequent causes of nosocomial and community-acquired infections, with drug-resistant strains being responsible for tens of thousands of deaths per year. S. aureus sortase A inhibitors are designed to interfere with virulence determinants. We
Udo H Verkerk et al.
The journal of physical chemistry. A, 115(24), 6683-6687 (2011-05-21)
Collision-induced dissociations of protonated (18)O-labeled tetraglycines labeled separately at either the first or the second amide bond established that water loss from the backbone occurs from the N-terminal residue. Density functional theory at B3LYP/6-311++G(d,p) predicted that the low-energy [G(4) +
María V Alipázaga et al.
Dalton transactions (Cambridge, England : 2003), (13)(13), 2036-2040 (2004-07-15)
The synergistic effect of Ni(II) and Co(II) on the sulfite induced autoxidation of Cu(II)/tetraglycine was investigated spectrophotometrically at 25.0 degrees C, pH = 9.0, 1 x 10(-5) mol dm(-3) < or = [S(IV)] < or = 8 x 10(-5) mol
K S Kasprzak et al.
Carcinogenesis, 10(3), 621-624 (1989-03-01)
This study was undertaken to explore whether nuclear chromatin constituents can participate in and/or be affected by redox reactions catalyzed by nickel, like those of nickel complexes with small peptides, e.g. tetraglycine (G4) and oxygen. Calf thymus DNA, nucleohistone (NH)
Yanfeng Yao et al.
Emerging microbes & infections, 8(1), 45-54 (2019-03-15)
Current influenza vaccines provide hemagglutinin strain-specific protection, but rarely provide cross-protection against divergent strains. It is, therefore, particularly important to develop a universal vaccine against conserved proteins or conserved regions of the virus. In this study, we used N-terminal extracellular

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