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Merck
CN

G2878

甘胆酸 水合物

synthetic, ≥97% (HPLC)

别名:

3α,7α,12α-三羟基-5β-胆甾烷-24-羧酸N-(羧甲基)酰胺, N-(3α,7α,12α-三羟基-24-氧代胆甾烷-24-基)-甘氨酸, 甘氨胆酸

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关于此项目

经验公式(希尔记法):
C26H43NO6 · xH2O
化学文摘社编号:
分子量:
465.62 (anhydrous basis)
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2955826
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产品名称

甘胆酸 水合物, synthetic, ≥97% (HPLC)

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

SMILES string

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI key

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

biological source

synthetic

description

anionic

assay

≥97% (HPLC)

form

powder

mol wt

average mol wt 1000

aggregation number

2.1

technique(s)

enzyme immunoassay: suitable

CMC

7.1

functional group

amide

shipped in

ambient

storage temp.

room temp

Quality Level

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Application

甘氨胆酸用于研究评估隐孢子虫属对培养细胞的侵袭性。 还用于研究壳聚糖和水包油乳剂在模拟消化系统条件下的相互作用。

Biochem/physiol Actions

胆汁酸

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Raj S Bhopal et al.
The lancet. Diabetes & endocrinology, 2(3), 218-227 (2014-03-14)
The susceptibility to type 2 diabetes of people of south Asian descent is established, but there is little trial-based evidence for interventions to tackle this problem. We assessed a weight control and physical activity intervention in south Asian individuals in
Yazhou He et al.
PloS one, 9(3), e91202-e91202 (2014-03-14)
Association between the single nucleotide polymorphism rs3218536 (known as Arg188His) located in the X-ray repair cross complementing group 2 (XRCC2) gene and cancer susceptibility has been widely investigated. However, results thus far have remained controversial. A meta-analysis was performed to
Konstantin Kazankov et al.
Hepatology (Baltimore, Md.), 60(2), 521-530 (2014-03-14)
Macrophages are involved in inflammation and liver fibrosis and soluble (s)CD163 is a specific marker of activated macrophages. We investigated associations between sCD163 and biochemical and histological parameters of inflammatory activity and fibrosis in 551 patients with chronic hepatitis C
Matthias Laska
Chemical senses, 39(5), 415-424 (2014-03-14)
Using a conditioning paradigm, the olfactory sensitivity of CD-1 mice for a homologous series of aliphatic 2-ketones (2-butanone to 2-nonanone) and several of their isomeric forms was investigated. With all 11 odorants, the animals significantly discriminated concentrations as low as
Examination of the Interaction of Chitosan and Oil-in-Water Emulsions Under Conditions Simulating the Digestive System Using Confocal Microscopy
Helgason, T., et al.
Journal of Aquatic Food Product Technology, 17, 216-233 (2008)

实验方案

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

相关内容

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

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