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Merck
CN

G2140

Sigma-Aldrich

L -氧化谷胱甘肽 二钠盐

suitable for cell culture, BioReagent

别名:

GSSG

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About This Item

经验公式(希尔记法):
C20H30N6Na2O12S2
分子量:
656.59
Beilstein:
6265389
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.75

生物来源

yeast

质量水平

产品线

BioReagent

检测方案

≥98%

形式

powder

技术

cell culture | mammalian: suitable

杂质

ethanol, essentially free

溶解性

water: 50 mg/mL, clear, colorless to very faintly yellow

储存温度

−20°C

SMILES字符串

[Na+].[Na+].N[C@@H](CCC(=O)N[C@@H](CSSC[C@H](NC(=O)CC[C@H](N)C([O-])=O)C(=O)NCC(O)=O)C(=O)NCC([O-])=O)C(O)=O

InChI

1S/C20H32N6O12S2.2Na/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38;;/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38);;/q;2*+1/p-2/t9-,10-,11-,12-;;/m0../s1

InChI key

DRFILBXQKYDTFW-JIWRMXRASA-L

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Amino Acid Sequence

(γ-Glu-Cys-Gly) (γ-Glu-Cys-Gly) [Disulfide bridge: 2a-2b]

应用

For use in cell culture applications as an antioxidant and heavy metal detoxification agent. L-Glutathione oxidized disodium salt has been used in semen processing and evaluation.

生化/生理作用

Oxidized L-glutathione is frequently measured in vivo as an indicator of oxidative stress.

相关产品

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

动植物源性产品

分析证书(COA)

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Influence of various antioxidants on microscopic-oxidative stress indicators and fertilizing ability of frozen-thawed bull semen
Sariozkan S, et al.
Acta Veterinaria Brno, 78(3), 463-469 (2009)
Oxidized forms of glutathione in peripheral blood as biomarkers of oxidative stress.
Rossi R
Clinical Chemistry, 52(7), 1406-1414 (2006)
Christian Stoppe et al.
Antioxidants & redox signaling, 23(11), 865-879 (2015-08-04)
Cardiac surgery involves myocardial ischemia/reperfusion (I/R) with potentially deleterious consequences. Macrophage migration inhibitory factor (MIF) is a stress-regulating chemokine-like cytokine that protects against I/R damage, but functional links with its homolog, d-dopachrome tautomerase (MIF-2), and the circulating soluble receptor CD74
Haitao Shi et al.
Journal of experimental botany, 66(3), 681-694 (2014-09-17)
Melatonin (N-acetyl-5-methoxytryptamine), a well-known animal hormone, is also involved in plant development and abiotic stress responses. In this study, it is shown that exogenous application of melatonin conferred improved salt, drought, and cold stress resistances in bermudagrass. Moreover, exogenous melatonin
Katia M S Gomes et al.
International journal of cardiology, 179, 129-138 (2014-12-03)
We previously demonstrated that reducing cardiac aldehydic load by aldehyde dehydrogenase 2 (ALDH2), a mitochondrial enzyme responsible for metabolizing the major lipid peroxidation product, protects against acute ischemia/reperfusion injury and chronic heart failure. However, time-dependent changes in ALDH2 profile, aldehydic

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