所有图片(1)
About This Item
经验公式（希尔记法）:
C12H21N3O6S
CAS号:
分子量:
335.38
MDL编号:
UNSPSC代码:
12161504
PubChem化学物质编号:
NACRES:
NA.26
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产品名称
还原型谷胱甘肽乙酯, ≥90% (TLC)
质量水平
方案
≥90% (TLC)
表单
powder
颜色
white to off-white
储存温度
−20°C
SMILES字符串
CCOC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@H](N)C(O)=O
InChI
1S/C12H21N3O6S/c1-2-21-10(17)5-14-11(18)8(6-22)15-9(16)4-3-7(13)12(19)20/h7-8,22H,2-6,13H2,1H3,(H,14,18)(H,15,16)(H,19,20)/t7-,8-/m0/s1
InChI key
JKRODHBGNBKZLE-YUMQZZPRSA-N
相关类别
Amino Acid Sequence
Glu-Cys-Gly-OEt
应用
还原型谷胱甘肽乙酯已被用于：
- 提高小鼠成纤维细胞 L929 细胞内谷胱甘肽水平
- 作为 果翅目昆虫 (Sf) 9 细胞的培养基补充
- 以评价其对脊髓损伤后脂质过氧化作用
生化/生理作用
谷胱甘肽乙酯（还原型）可通过抑制Melan-A细胞中的酪氨酸酶活性来抑制黑色素合成。它的抗黑色素生成功能可用于治疗皮肤色素沉着过度性疾病。从胰腺分离胰岛时，添加谷胱甘肽乙酯(GEE)可减少活性氧物质生成和细胞凋亡。
还原型谷胱甘肽乙酯 (GSH—MEE) 是 GSH 的膜/脂质渗透性衍生物，可用于部分补充细胞内遭受半胱氨酸和/或 GSH 耗竭的 GSH 供应。GSH-MEE 被细胞内酯酶水解释放 GSH，从而增加细胞内 GSH 的浓度。 防止动物细胞中对乙酰氨基酚的毒性作用。保护人体淋巴细胞和皮肤成纤维细胞免受辐射造成的损伤。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model
do Amaral ASR, et al.
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M E Anderson et al.
Archives of biochemistry and biophysics, 239(2), 538-548 (1985-06-01)
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Monteiro F, et al.
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