G1166
Anti-GAD65 Antibody
mouse monoclonal, GAD-6
别名:
Anti-GAD 65
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关于此项目
Conjugate:
unconjugated
Clone:
GAD-6, monoclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
mammals (and some lower vertebrates)
Citations:
11
Technique(s):
immunohistochemistry: 1:100-1:500
western blot: 1:1,000-1:5,000
western blot: 1:1,000-1:5,000
产品名称
Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse, clone GAD-6, purified immunoglobulin, buffered aqueous solution
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
GAD-6, monoclonal
form
buffered aqueous solution
species reactivity
mammals (and some lower vertebrates)
technique(s)
immunohistochemistry: 1:100-1:500
western blot: 1:1,000-1:5,000
isotype
IgG2a
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GAD2(2572)
mouse ... Gad2(14417)
Biochem/physiol Actions
Recognizes the lower molecular weight isoform of the two GAD isoforms identified in brain, GAD 65. Can be used for immunochemical localization of GABA secreting neurons.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
purified rat brain GAD 65.
Physical form
Solution in 0.01 M phosphate buffered saline, containing 0.04% sodium azide.
Preparation Note
Purified using Protein A chromatography.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Stathis S Leondopulos et al.
Journal of neural engineering, 9(2), 026015-026015 (2012-03-01)
Slow wave oscillations in the brain are essential for coordinated network activity but have not been shown to self-organize in vitro. Here, the development of dissociated hippocampal neurons into an active network with oscillations on multi-electrode arrays was evaluated in
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
Azadeh Yazdan-Shahmorad et al.
eLife, 7 (2018-05-29)
Brain stimulation modulates the excitability of neural circuits and drives neuroplasticity. While the local effects of stimulation have been an active area of investigation, the effects on large-scale networks remain largely unexplored. We studied stimulation-induced changes in network dynamics in
Rossella De Cegli et al.
Nucleic acids research, 41(2), 711-726 (2012-11-28)
Gene expression profiles can be used to infer previously unknown transcriptional regulatory interaction among thousands of genes, via systems biology 'reverse engineering' approaches. We 'reverse engineered' an embryonic stem (ES)-specific transcriptional network from 171 gene expression profiles, measured in ES
Susanna Molas et al.
Nature neuroscience, 20(9), 1260-1268 (2017-07-18)
Novelty preference (NP) is an evolutionarily conserved, essential survival mechanism often dysregulated in neuropsychiatric disorders. NP is mediated by a motivational dopamine signal that increases in response to novel stimuli, thereby driving exploration. However, the mechanism by which once-novel stimuli
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