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腺苷 5′-三磷酸腺苷 (ATP) 二钠盐 水合物
≥90%, bacterial (Corynebacterium sp), lyophilized powder
别名:
ATP 二钠 水合物
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关于此项目
线性分子式:
C10H14N5O13P3Na2 · xH2O
化学文摘社编号:
分子量:
551.14 (anhydrous basis)
UNSPSC Code:
12352202
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.26
EC Number:
213-579-1
MDL number:
产品名称
腺苷 5′-三磷酸腺苷 (ATP) 二钠盐 水合物, vial of ~1 mg ATP
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key
NTBQNWBHIXNPRU-MSQVLRTGSA-L
biological source
bacterial (Corynebacterium sp)
assay
≥90%
form
lyophilized powder
packaging
vial of ~1 mg ATP
solubility
water: soluble, clear, colorless (1 vial + 0.1 mL)
storage temp.
−20°C
Quality Level
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Application
腺苷5′-三磷酸盐(ATP)二钠盐水合物用作：
- 生物发光法测定ATP的标准物
- 激酶缓冲液，以评估死亡相关蛋白激酶(DAPK2)与14-3-3-β之间的相互作用
- ATP比色测定的标准
Biochem/physiol Actions
5′-三磷酸腺苷通过清除TNF-α的分泌和促进白介素-10的分泌，发挥对炎症反应的抑制作用。
P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物
腺苷5′-三磷酸(ATP)是存在于生命系统中的一种核苷三磷酸。它控制着各种生物过程，如葡萄糖代谢、肌肉收缩和神经传递等。除此之外，ATP还是细胞重要的能量来源。ATP的应用对非小细胞肺癌的治疗可能有用。
Preparation Note
制备过程基本无钒。
每小瓶含 ~1.2mg Na2ATP • 3H2O，相当于 ~1.0mg ATP (2.0μmol)。标签上印有实际含量。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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In vitro studies suggest that extracellular nucleotides and nucleosides may be important regulators of inflammatory and immune responses. Most studies with adenosine 5'-triphosphate (ATP) have been performed in cell lines, which are remote from the human situation. The purpose of
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