推荐产品
生物来源
rabbit
质量水平
偶联物
FITC conjugate
抗体形式
IgG fraction of antiserum
抗体产品类型
secondary antibodies
克隆
polyclonal
表单
buffered aqueous solution
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:160
indirect immunofluorescence: 1:200
储存温度
−20°C
靶向翻译后修饰
unmodified
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一般描述
The immunoglobulin G (IgG) is a major class of immunoglobulin and is highly conserved. IgG constitutes to 10−20% of the plasma proteins. This class of immunoglobulins are glycoproteins containing 82−96% protein and the remaining, carbohydrate. It exists in four subclasses namely, IgG1, IgG2, IgG3, and IgG4. IgG is composed of four polypeptide chains containing two heavy and two light chains, linked by disulfide bonds.
特异性
The antiserum is determined to be immunospecific for goat IgG.
应用
Anti-Goat IgG (whole molecule)-FITC antibody produced in rabbit has been used for immunocytochemistry of human oocytes and preimplantation embryos.
It has also been used in enzyme linked immunosorbent assay (ELISA) and confocal microscopy.
生化/生理作用
Deficiency of a particular IgG subclass, may increase the susceptibility towards certain pathogens.
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. The coupling of FITC to Anti- Goat IgG (whole molecule) antibody allows for the visualization of protein by fluorescent microscopy.
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
储存及稳定性
For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
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