一般描述
该产品可结合人IgM；但不与其他人Igs结合。
应用
山羊源抗-人IgM（μ-链特异性）-FITC抗体可用作莱姆病血清诊断（基于针对Borrelia藻血清反应）的二抗。
生化/生理作用
IgM抗体在血清中以五聚体的形式存在，为响应抗原而产生。
外形
0.01 M 磷酸盐缓冲液 (pH 7.4) 中的溶液，含 1% 牛血清白蛋白和 15 mM 叠氮化钠
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Nayoung Ko et al.
Scientific reports, 12(1), 9611-9611 (2022-06-11)
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Ablation
Miriam Casacuberta-Partal et al.
Journal of travel medicine, 27(4) (2020-04-21)
Travellers infected with Schistosoma spp. might be pauci- or even asymptomatic on first presentation. Therefore, schistosomiasis may remain undiagnosed in this population. Active infection, as evidenced by the presence of the tissue-dwelling worm, can be demonstrated via the detection of
J C Magee et al.
The Journal of clinical investigation, 96(5), 2404-2412 (1995-11-01)
Immunoglobulins regulate the complement system by activating complement on foreign surfaces and diverting reactive complement proteins away from autologous cell surfaces. Based on this model, we explored the ability of Ig to balance complement activation versus control in a pig-to-primate
Julia Hennicke et al.
New biotechnology, 50, 20-26 (2019-01-11)
IgM antibodies are arousing considerable interest as biopharmaceuticals. Despite their immunotherapeutic potential, little is known about the impact of environmental conditions on product quantity and quality of these complex molecules. Process conditions influence the critical quality attributes (CQAs) of therapeutic
Clayton A White et al.
Journal of immunology (Baltimore, Md. : 1950), 193(12), 5933-5950 (2014-11-14)
Class-switch DNA recombination (CSR) and somatic hypermutation (SHM), which require activation-induced cytidine deaminase (AID), and plasma cell differentiation, which requires B lymphocyte-induced maturation protein-1 (Blimp-1), are critical for the generation of class-switched and hypermutated (mature) Ab and autoantibody responses. We
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