推荐产品
产品名称
间氟-DL-酪氨酸,
方案
≥98%
质量水平
表单
powder
技术
ligand binding assay: suitable
颜色
white
mp
280 °C (dec.) (lit.)
储存温度
2-8°C
SMILES字符串
NC(Cc1ccc(O)c(F)c1)C(O)=O
InChI
1S/C9H10FNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)
InChI key
VIIAUOZUUGXERI-UHFFFAOYSA-N
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生化/生理作用
M-Fluorotyrosine (m-Fluoro-DL-tyrosine) may be substituted for tyrosine in the biosynthesis of proteins such as β-galactosidases (Escherichia coli), bacteriorhodopsin and intestinal microvillar enzymes, eg. aminopeptidase N, to study the effect of halogenated tryosines on the proteins properties.
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Julianne L Kitevski-LeBlanc et al.
Journal of biomolecular NMR, 45(3), 255-264 (2009-08-06)
Fluorine NMR is a useful tool to probe protein folding, conformation and local topology owing to the sensitivity of the chemical shift to the local electrostatic environment. As an example we make use of (19)F NMR and 3-fluorotyrosine to evaluate
Mohammad R Seyedsayamdost et al.
Nature protocols, 2(5), 1225-1235 (2007-06-05)
Expressed protein ligation (EPL) allows semisynthesis of a target protein with site-specific incorporation of probes or unnatural amino acids at its N or C termini. Here, we describe the protocol that our lab has developed for incorporating fluorotyrosines (F(n)Ys) at
Julianne L Kitevski-LeBlanc et al.
Journal of the American Chemical Society, 131(6), 2054-2055 (2009-01-29)
Solution NMR studies of protein structure and dynamics using fluorinated amino acid probes are a valuable addition to the repertoire of existing (13)C, (15)N, and (1)H experiments. Despite the numerous advantages of the (19)F nucleus in NMR, protein studies are
Crystallographic evidence for isomeric chromophores in 3-fluorotyrosyl-green fluorescent protein.
Jae Hyun Bae et al.
Chembiochem : a European journal of chemical biology, 5(5), 720-722 (2004-05-04)
M Ring et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 71(3-4), 127-132 (1993-03-01)
An Escherichia coli tyrosine auxotroph (MR1) with an inducible lacZ was generated by mutagenesis. Of several tyrosine derivatives tested, only m-fluorotyrosine supported the growth of this mutant and allowed synthesis of active beta-galactosidase. The pH profiles of the beta-galactosidase that
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