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安全信息

F3627

Sigma-Aldrich

D-果糖6-磷酸 二钠盐 水合物

≥98%, amorphous powder

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别名:
Sodium (2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl phosphate
经验公式（希尔记法）:
C6H11Na2O9P · xH2O
CAS号:
26177-86-6
分子量:
304.10 (anhydrous basis)
Beilstein:
5686786
MDL编号:
MFCD16661244
UNSPSC代码:
12352201
PubChem化学物质编号:
329799699
NACRES:
NA.25

生物来源

bacterial (Corynebacterium)

质量水平

300

检测方案

≥98%

形式

amorphous powder

杂质

<0.05 mol % fructose 1,6-diphosphate
<1.5 mol % glucose 6-phosphate

颜色

white to off-white

溶解性

H2O: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

痕量阳离子

Na: 14.6-15.6% (dry basis)

应用

agriculture

储存温度

−20°C

SMILES字符串

O.[Na+].[Na+].OC[C@@]1(O)O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13;;;/h3-5,7-10H,1-2H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t3-,4-,5+,6-;;;/m1.../s1

InChI key

VSCMQICEHMPOEC-HTKRKRNRSA-L

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相关类别

应用

D-果糖-6-磷酸（F6P）是糖酵解途径的糖中间体，可用于帮助鉴定、区分和表征一些酶，例如磷酸果糖激酶、焦磷酸依赖性果糖-6-磷酸1-磷酸转移酶、D-果糖6-磷酸醛缩酶、谷氨酰胺：果糖-6-磷酸酰胺转移酶和葡糖胺6P合酶。

生化/生理作用

6-磷酸果糖是通过磷酸葡萄糖异构酶将6-磷酸葡萄糖异构化而产生的糖酵解中间体。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319

危险分类

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Kay O Broschat et al.
The Journal of biological chemistry, 277(17), 14764-14770 (2002-02-14)
Glutamine-fructose-6-phosphate amidotransferase (GFAT) catalyzes the first committed step in the pathway for biosynthesis of hexosamines in mammals. A member of the N-terminal nucleophile class of amidotransferases, GFAT transfers the amino group from the L-glutamine amide to D-fructose 6-phosphate, producing glutamic
Yimin Qian et al.
Bioorganic & medicinal chemistry letters, 21(21), 6264-6269 (2011-10-01)
Through high throughput screening and subsequent hit identification and optimization, we synthesized a series of 1-arylcarbonyl-6,7-dimethoxyisoquinoline derivatives as the first reported potent and reversible GFAT inhibitors. SAR studies of this class of compounds indicated significant impact on GFAT inhibition potency
O N Rozova et al.
Biochemistry. Biokhimiia, 77(3), 288-295 (2012-07-19)
The properties of the purified recombinant PPi-dependent 6-phosphofructokinases (PPi-PFKs) from the methanotroph Methylosinus trichosporium OB3b and rhizospheric phytosymbiont Methylobacterium nodulans ORS 2060 were determined. The dependence of activities of PPi-PFK-His(6)-tag from Ms. trichosporium OB3b (6 × 45 kDa) and PPi-PFK from
Sławomir Milewski
Biochimica et biophysica acta, 1597(2), 173-192 (2002-06-05)
L-Glutamine: D-fructose-6-phosphate amidotransferase, known under trivial name of glucosamine-6-phosphate synthase, as the only member of the amidotransferase subfamily of enzymes, does not display any ammonia-dependent activity. This enzyme, catalysing the first committed step in a pathway leading to the eventual
María Cruz Rodríguez et al.
PloS one, 7(12), e50876-e50876 (2012-12-29)
Bacteria of the genus Brucella have the unusual capability to catabolize erythritol and this property has been associated with their virulence mainly because of the presence of erythritol in bovine foetal tissues and because the attenuated S19 vaccine strain is
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