E6005
乙硫磷酰胺
≥98.0%, suitable for ligand binding assays
别名:
2-乙基-4-吡啶羧基硫代酰胺
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关于此项目
经验公式（希尔记法）:
C8H10N2S
化学文摘社编号:
分子量:
166.24
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352111
EC Number:
208-628-9
MDL number:
产品名称
乙硫磷酰胺,
assay
≥98.0%
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
yellow
storage temp.
2-8°C
SMILES string
CCc1cc(ccn1)C(N)=S
InChI
1S/C8H10N2S/c1-2-7-5-6(8(9)11)3-4-10-7/h3-5H,2H2,1H3,(H2,9,11)
InChI key
AEOCXXJPGCBFJA-UHFFFAOYSA-N
General description
乙硫异烟胺 (ETA，ETH) 是一种硫代酰胺 ，是一种抗结核药，在其他药物无效时，可作为二线治疗药物用于治疗结核病。 ETA 的结构与异烟肼相似。
Application
乙硫异烟胺用于抗菌剂 和测试化合物对 结核分枝杆菌的效价测定 。
Biochem/physiol Actions
乙硫异烟胺用作抗结核抗生素和甲状腺功能减退的诱导剂。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Liang-Chun Chen et al.
BMC systems biology, 6, 5-5 (2012-01-20)
Drug resistance has now posed more severe and emergent threats to human health and infectious disease treatment. However, wet-lab approaches alone to counter drug resistance have so far still achieved limited success due to less knowledge about the underlying mechanisms
Joan M Korth-Bradley et al.
Clinical therapeutics, 36(6), 982-987 (2014-05-17)
Ethionamide sugar-coated tablets have been reformulated to film-coated tablets to improve dissolution and stability. The study objective was to compare the bioavailability of the film-coated (test) and sugar-coated (reference) formulations of ethionamide. After providing informed consent and undergoing screening procedures
Catherine Vilchèze et al.
Antimicrobial agents and chemotherapy, 55(9), 4422-4423 (2011-06-29)
A search to identify new mechanisms of isoniazid resistance in Mycobacterium bovis led to the isolation of mutants defective in mycothiol biosynthesis due to mutations in genes coding for the glycosyltransferase (mshA) or the cysteine ligase (mshC). These mutants showed
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E6005-25G | 04061832416229 |
| E6005-5G | 04061833604427 |
| E6005-100G | 04061833604410 |