所有图片(4)
About This Item
经验公式(希尔记法):
C10H14N5O7P · xNa+ · yH2O
分子量:
347.22 (anhydrous free acid basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
推荐产品
质量水平
方案
≥99% (HPLC)
表单
powder
溶解性
water: 50 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
O.[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP(O)([O-])=O)O3)C(=O)N1
InChI
1S/C10H14N5O7P.Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;1H2/q;+1;/p-1/t4-,5+,6+;;/m0../s1
InChI key
UVKXYXSKMTUDML-FVALZTRZSA-M
应用
2′-脱氧鸟苷5′-单磷酸酯(dGMP)用作鸟苷酸激酶(EC 2.7.4.8)的底物,形成dGDP,磷酸化为dGTP后可支持DNA生物合成。dGMP用于研究鸟嘌呤类分子的理化特性。
2′-脱氧鸟苷5′-单磷酸钠盐水合物已被用于:
- 反相高压力液相色谱(HPLC)分析
- 确定脱氧单核苷酸对自发增殖的CaCo-2细胞系的影响
- 确定其刺激免疫细胞生长和功能的能力,并在体外使用流行性感冒病毒抗原作为免疫刺激剂
储存分类代码
11 - Combustible Solids
WGK
WGK 3
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Mahmoud Kandeel et al.
Molecular and biochemical parasitology, 159(2), 130-133 (2008-04-01)
The present work describes cloning, expression, purification, characterization, and mutation of Plasmodium falciparum guanylate kinase (PlasmoDB ID PFI1420w). Amino-acid sequence alignment revealed important differences especially in K42-V51, Y73-A77, and F100-L110, which include residues important for kinase activity, and at helix
Brian G Gentry et al.
Biochemical pharmacology, 81(1), 43-49 (2010-09-18)
Many fraudulent nucleosides including the antivirals acyclovir (ACV) and ganciclovir (GCV) must be metabolized to triphosphates to be active. Cyclopropavir (CPV) is a newer, related guanosine nucleoside analog that is active against human cytomegalovirus (HCMV) in vitro and in vivo.
Dietary nucleotides and intestinal cell lines: I. Modulation of growth
Holen E and Jonsson R
Nutrition Research (New York, N.Y.), 24(3), 197-207 (2004)
Ana-Maria Ruxandra Eftimie et al.
Roumanian archives of microbiology and immunology, 66(1-2), 22-25 (2008-10-22)
Guanylate kinase is a member of the nucleoside monophosphate (NMP) kinase family, a family of enzymes that despite having a low primary structure identity share a similar fold, which consists of three structurally distinct regions termed the CORE, LID, and
Global DNA methylation as a possible biomarker for diabetic retinopathy
Maghbooli Z, et al.
Diabetes/metabolism Research and Reviews, 31(2), 183-189 (2015)
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