质量水平
检测方案
≥98% (HPLC)
形式
solid
储存条件
protect from light
颜色
white
溶解性
DMSO: >20 mg/mL
SMILES字符串
NC(=O)COc1c(F)cc(SCCNS(=O)(=O)c2ccccc2)cc1F
InChI
1S/C16H16F2N2O4S2/c17-13-8-11(9-14(18)16(13)24-10-15(19)21)25-7-6-20-26(22,23)12-4-2-1-3-5-12/h1-5,8-9,20H,6-7,10H2,(H2,19,21)
InChI key
GTACSIONMHMRPD-UHFFFAOYSA-N
基因信息
human ... GRIA1(2890) , GRIA2(2891) , GRIA3(2892) , GRIA4(2893)
生化/生理作用
2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide is a structurally novel, selective, high affinity AMPA ionotropic glutamate receptor agonist that reduces ischemia-induced performance deficits in rats.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Weisheng Chen et al.
Neuroscience letters, 612, 126-131 (2015-12-08)
Infralimbic cortex (IL) is proposed to suppress cocaine seeking after extinction, but whether the IL regulates the extinction and reinstatement of heroin-seeking behavior is unknown. To address this issue, the male SD rats were trained to self-administer heroin under a
Amirbek Bekeshev et al.
Polymers, 12(7) (2020-07-02)
The conducted studies have proven the possibility of the directed control of operational properties of epoxy composites, due to the addition of finely-ground ocher into their composition, and the use of microwave modification of the epoxy composition. The rational content
Clarissa Perez Faria et al.
Scientific reports, 10(1), 6234-6234 (2020-04-12)
The protozoan Giardia lamblia is the most common cause of parasitic gastrointestinal infection worldwide. The parasite developed sophisticated, yet not completely disclosed, mechanisms to escape immune system and growth in the intestine. To further understand the interaction of G. lamblia
Yanchao Xu et al.
Journal of colloid and interface science, 565, 23-34 (2020-01-14)
Nanofiltration (NF) membranes with tannic acid (TA) based selective layers have been intensively studied in recent years, but they still suffer from poor inorganic salt rejection. This study provided a first report on mussel-inspired co-deposition of TA and amine to
Quan-Guang Zhang et al.
Hippocampus, 20(1), 65-77 (2009-03-31)
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are responsible for excitotoxicity induced by ischemic injury in hippocampal CA1 neurons, whereas the molecular mechanisms responsible for their neurotrophic activities are much less studied. Here, we examined the neuroprotective effect of positive modeulation of AMPARs
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