GRIA4
glutamate receptor, ionotropic, AMPA 4
GLUR4, GLUR4C, GLURD, GluA4
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), sheep GRIA4 (443274), domestic cat GRIA4 (101087003), chicken GRIA4 (396137), domestic guinea pig Gria4 (100728256), cow GRIA4 (529904), Horse GRIA4 (100061561), dog GRIA4 (489427)
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
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Custom Gene Products
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Small Molecule - Antagonist
Antibodies
Anti-Gria4 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
抗谷氨酸受体4抗体, Chemicon®, from rabbit,
mouse, rat
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
western blot
western blot
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
mouse, rat
western blot
Anti-GRIA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
bovine, human, mouse, rat
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
human