所有图片(2)
About This Item
经验公式（希尔记法）:
C9H15N3O10P2 · xNa+
CAS号:
分子量:
387.18 (free acid basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
推荐产品
质量水平
方案
≥96%
表单
powder
储存温度
−20°C
SMILES字符串
O.[Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(=O)OP(O)(O)=O)O2
InChI
1S/C9H15N3O10P2.Na.H2O.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(21-8)4-20-24(18,19)22-23(15,16)17;;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H2,10,11,14)(H2,15,16,17);;1H2;
InChI key
MNOALMYIRLFAQW-UHFFFAOYSA-N
相关类别
应用
2′-脱氧胞苷5′-二磷酸（dCDP）已被用作核苷酸二磷酸激酶（NDPK）的底物，以产生2′-脱氧胞苷5′-三磷酸（dCTP），以支持DNA生物合成和逆转录。
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
High glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cells
Hu CM, et al.
Cell Metabolism, 29(6), 1334-1349 (2019)
Hüseyin Besir et al.
FEBS letters, 579(29), 6595-6600 (2005-11-19)
Nucleoside diphosphate kinase from the halophilic archaeon Halobacterium salinarum was crystallized in a free state and a substrate-bound form with CDP. The structures were solved to a resolution of 2.35 and 2.2A, respectively. Crystals with the apo-form were obtained with
Argirios Siskos et al.
Journal of plant physiology, 167(9), 675-682 (2010-03-02)
Two isoforms of NDPKs (diphosphonucleoside kinases: E.C. 2.7.4.6.) named S-NDPK-A and S-NDPK-B were separated and purified from shoots of Alyssum murale (19th day of growth), a nickel accumulator plant, by a four-step procedure involving ammonium sulphate precipitation and DEAE-sepharose and
Dimitri Topalis et al.
Nucleosides, nucleotides & nucleic acids, 26(10-12), 1369-1373 (2007-12-11)
Human UMP-CMP kinase is involved in the phosphorylation of nucleic acid precursors and also in the activation of antiviral analogues including cidofovir, an acyclic phosphonate compound that mimicks dCMP and shows a broad antiviral spectrum. The binding of ligands to
Mahmoud Kandeel et al.
Journal of bioenergetics and biomembranes, 42(5), 361-369 (2010-08-17)
Nucleoside diphosphate kinases (NDKs) play a key role in maintaining the intracellular energy resources as well as the balance of nucleotide pools. Recently, attention has been directed to NDKs owing to its role in activating various chemotherapeutic agents. The binding
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