所有图片(3)
About This Item
经验公式(希尔记法):
C10H14N5Na2O12P3
CAS号:
分子量:
535.15
EC 号:
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51
推荐产品
生物来源
natural (inorganic)
质量水平
方案
≥97%
表单
powder
储存温度
−20°C
SMILES字符串
[Na+].[Na+].Nc1ncnc2n(cnc12)C3C[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)O3
InChI
1S/C10H16N5O12P3.2Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);;/q;2*+1/p-2/t5-,6+,7?;;/m0../s1
InChI key
JEKDCIBJADJZSK-LNUHRGGJSA-L
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相关类别
应用
2′-脱氧腺苷 5′-三磷酸二钠盐已用于:
- Smac-X-连锁凋亡蛋白抑制剂(Smac-XIAP)结合试验。
- 作为聚合酶链式反应 (PCR) 的组成部分,使用 AM-毒素引物。
- 测定与转录终止因子Rho的亲和常数 (Kd)。
- 测定多聚 ADP-核糖聚合酶1(PAPR-1)的活性。
2'-脱氧腺苷-5'-三磷酸 (dATP) 被多种聚合酶(包括 DNA 聚合酶和逆转录酶)用作底物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA
Gemble S, et al.
PLoS Genetics, 11(7), e1005384-e1005384 (2015)
Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64
Cheng J, et al.
American Journal of Human Genetics, 89(1), 56-66 (2011)
Michael Trostler et al.
Biochemistry, 48(21), 4633-4641 (2009-04-08)
We used a series of dATP and dGTP analogues to determine how DNA polymerase I from Bacillus stearothermophilus (BF), a prototypical A family polymerase, uses N-1, N(2), N-3, and N(6) of purine dNTPs to differentiate between right and wrong nucleotide
Fadia Haddad et al.
Methods in molecular biology (Clifton, N.J.), 630, 261-270 (2010-03-20)
Reverse transcription (RT) is the synthesis of complementary deoxyribonucleic acids (DNA) from single-stranded ribonucleic acid (RNA) templates. This process is catalyzed by the reverse transcriptase enzyme, which is the replicating enzyme of retroviruses. Reverse transcriptase was discovered in 1970, and
J E Reardon
Biochemistry, 31(18), 4473-4479 (1992-05-12)
Steady-state and pre-steady-state kinetic constants were determined for reverse transcriptase catalyzed incorporation of nucleotides and nucleotide analogues into defined-sequence DNA primed-RNA templates. 3'-Azido-3'-deoxythymidine 5'-triphosphate (AZTTP) was almost as efficient a substrate (kcat/Km) as dTTP for the enzyme. In contrast, the
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