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检测方案
≥99%
质量水平
形式
liquid
浓度
100 mM
颜色
colorless
pH值（酸碱度）
7
异质活性
DNase, RNase, none detected
运输
dry ice
储存温度
−20°C
SMILES字符串
[Na+].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)([O-])=O)O3
InChI
1S/C10H16N5O12P3.Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(25-7)2-24-29(20,21)27-30(22,23)26-28(17,18)19;/h3-7,16H,1-2H2,(H,20,21)(H,22,23)(H2,11,12,13)(H2,17,18,19);/q;+1/p-1/t5-,6+,7+;/m0./s1
InChI key
YJWCICGGRLOGEH-VWZUFWLJSA-M
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相关类别
一般描述
2′-脱氧腺苷5′-三磷酸（dATP）由脱氧核糖上的一个碱基和糖上与一个由三个磷酸残基组成的链相结合的糖上的5′-羟基组成。细胞利用dATP通过DNA聚合酶合成DNA。
应用
2′-脱氧腺苷5′-三磷酸盐钠盐可用于DNA合成反应，如PCR、DNA测序和分子克隆技术。
2′-脱氧腺苷5′-三磷酸钠盐水已用于通过末端脱氧核苷酸转移酶dUTP缺口末端标记（TUNEL）技术检测凋亡细胞。还用于促进凋亡蛋白酶活化因子-1(Apaf-1)寡聚化形成名为凋亡体或Apaf-1 procaspase-9凋亡体复合物的七聚体大复合体，并用于研究其基于蛋白降解的分子计时器功能。
组分
T4 DNA连接酶以溶于20 mM Tris-HCl（pH 7.5），50 mM KCl，1 mM DTT和50%（v/v）甘油的溶液形式提供。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Jager W, et al.
Testing, 8(3), e59536-e59536 (2013)
Srinivas Malladi et al.
The EMBO journal, 28(13), 1916-1925 (2009-06-06)
During stress-induced apoptosis, the initiator caspase-9 is activated by the Apaf-1 apoptosome and must remain bound to retain significant catalytic activity. Nevertheless, in apoptotic cells the vast majority of processed caspase-9 is paradoxically observed outside the complex. We show herein
Anders Hofer et al.
Critical reviews in biochemistry and molecular biology, 47(1), 50-63 (2011-11-05)
Ribonucleotide reductase (RNR) is the only source for de novo production of the four deoxyribonucleoside triphosphate (dNTP) building blocks needed for DNA synthesis and repair. It is crucial that these dNTP pools are carefully balanced, since mutation rates increase when
Kevin N Kirouac et al.
Nucleic acids research, 41(3), 2060-2071 (2012-12-27)
Nitrated polycyclic aromatic hydrocarbons are common environmental pollutants, of which many are mutagenic and carcinogenic. 1-Nitropyrene is the most abundant nitrated polycyclic aromatic hydrocarbon, which causes DNA damage and is carcinogenic in experimental animals. Error-prone translesion synthesis of 1-nitropyrene-derived DNA
F S Korte et al.
Journal of molecular and cellular cardiology, 51(6), 894-901 (2011-09-20)
We have previously demonstrated that substitution of ATP with 2 deoxy-ATP (dATP) increased the magnitude and rate of force production at all levels of Ca(2+)-mediated activation in demembranated cardiac muscle. In the current study we hypothesized that cellular [dATP] could
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