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Merck
CN

D4641

Sigma-Aldrich

十二烷基β-D-麦芽糖苷

≥98% (GC)

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别名:
DDM, 月桂基-β-D-麦芽糖苷
经验公式(希尔记法):
C24H46O11
CAS号:
分子量:
510.62
Beilstein:
55318
MDL编号:
UNSPSC代码:
12161900
eCl@ss:
32190102
PubChem化学物质编号:
NACRES:
NA.25

生物来源

corn

质量水平

描述

non-ionic

检测方案

≥98% (GC)

形式

powder

分子量

micellar avg mol wt 50,000

聚集数

98

技术

protein quantification: suitable

杂质

<1.5% water (Karl Fischer)

CMC

0.15 mM (20-25°C)

mp

224-226 °C (lit.)

溶解性

water: 50 mg/mL, clear to very slightly hazy, colorless

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

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一般描述

十二烷基-β-D-麦芽糖苷(N-dodecyl-β-D-maltoside)也称为月桂酰基麦芽糖苷,是一种非离子型表面活性剂和芘(Py)衍生物。作为烷基麦芽吡喃糖苷去污剂,对膜蛋白的溶解和结晶效用优异,是细胞生物学和生物化学研究的重要工具。它的独特性在于容易形成类似膜环境的胶束,从而维持膜结合蛋白的α-螺旋结构和天然构象。

十二烷基-β-D-麦芽糖苷还有其他多种用途,包括纯化和稳定RNA聚合酶、检测蛋白-脂质互作、作为糖原蛋白(glycogenin)催化葡萄糖基和木糖苷转移的底物。温和、非变性的特性适合蛋白-麻醉研究。总而言之,十二烷基-β-D-麦芽糖苷是一种多功能的去污剂,在膜蛋白等研究领域应用广泛。它维持蛋白结构和功能的重要特性令其成为膜生物学精细探索不可或缺的工具。

应用

正十二烷基β-D-麦芽糖甙已被用于一项研究,以评估通过GPS-NMR和散射技术映射整体螺旋膜蛋白的展开状态。
非离子型去污剂,用于酶的稳定和活化以及用于膜研究。

特点和优势

  • 功能丰富的表面活性剂,适于细胞生物学和生物化学研究
  • 适于蛋白定量

其他说明

For additional information on our range of Biochemicals, please complete this form.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

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