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Merck
CN

D4010

Sigma-Aldrich

2′-脱氧鸟苷5′-三磷酸 钠盐 水合物

≥96% (HPLC)

别名:

2′-脱氧-, 5′-三磷酸钠盐, 鸟苷, dGTP 钠盐 水合物

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About This Item

经验公式(希尔记法):
C10H16N5O13P3 · xNa+ · yH2O
CAS号:
分子量:
507.18 (anhydrous free acid basis)
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

生物来源

synthetic (organic)

质量水平

检测方案

≥96% (HPLC)

形式

powder

运输

dry ice

储存温度

−20°C

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相关类别

应用

2′-脱氧鸟苷5′-三磷酸钠盐水合物已用于:
  • 用作聚合酶链式反应 (PCR) 混合物中的一种成分,使用AM-毒素引物形成 PCR 产物
  • 用作内标,提高毛细管电泳 (CE) 分析的分析性能,评估纯化工艺
  • 用作体外酶活性测定中的推定底物,与Nudix水解酶 15 (NUDT15) 蛋白一起孵育,评估推定的 NUDT15 抑制剂

生化/生理作用

脱氧鸟苷5′-三磷酸(dGTP),一种嘌呤脱氧核糖核苷酸,是DNA聚合酶和逆转录酶的底物。 dGTP可用于研究各种核苷三磷酸酶(NTPase)和核糖核苷酸还原酶的分布、特异性和动力学。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)


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