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Merck
CN

D4001

Sigma-Aldrich

2′-脱氧尿苷 5′-三磷酸 钠盐

≥95%

别名:

dUTP 钠盐

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About This Item

经验公式(希尔记法):
C9H15N2O14P3 · xNa+
分子量:
468.14 (free acid basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

生物来源

synthetic (organic)

质量水平

方案

≥95%

表单

powder

储存温度

−20°C

SMILES字符串

[Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;

InChI key

FVFWWPFKJNTHIQ-UHFFFAOYSA-N

相关类别

应用

2′-脱氧尿苷5′-三磷酸钠盐已用于从非洲cat鱼中提取白肌肉。
2′-脱氧尿苷5′-三磷酸(dUTP)可用于研究脱氧尿苷5′-三磷酸核苷酸水解酶(dUTPase,EC 3.6.1.23)的分布,特异性和动力学。dUTPase是保护细胞免受dUTP掺入DNA的重要酶。dUTP是TUNEL(末端脱氧核糖核苷酸转移酶(TdT)介导的脱氧尿苷-5′-三磷酸(dUTP)缺口末端标记)测试的组成部分。TUNEL是检测凋亡信号级联反应导致的DNA片段化的常用方法。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

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Lucy Freeman et al.
The Journal of biological chemistry, 284(37), 25280-25289 (2009-07-10)
Deoxyuridine 5'-triphosphate pyrophosphatases (dUTPases) are ubiquitous enzymes essential for hydrolysis of dUTP, thus preventing its incorporation into DNA. Although Epstein-Barr virus (EBV) dUTPase is monomeric, it has a high degree of similarity with the more frequent trimeric form of the
Claudia Ulbrich et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26(6), 1011-1022 (2011-01-12)
Myocardium is very sensitive to gravitational changes. During a spaceflight cardiovascular atrophy paired with rhythm problems and orthostatic intolerance can occur. The aim of this study was to investigate the impact of basic fibroblast growth factor (bFGF) and vascular endothelial
Kwou-Yeung Wu et al.
Molecular vision, 14, 1705-1712 (2008-09-23)
Previous studies have indicated that improper use of mitomycin C (MMC) caused cytotoxicity in corneal endothelial cells. The aim of the present study was to investigate whether MMC induces cellular apoptosis in corneal endothelial cells and to determine the mechanism
Alexandra Kalogeraki et al.
Acta cytologica, 54(1), 39-42 (2010-03-24)
To evaluate apoptosis and cell proliferation on cytologic specimens (smears) from endoscopic retrograde cholangiopancreatography in patients with ampulary carcinoma and to correlate that relationship with the grade of the tumors. Forty patients (23 males and 17 females) aged 45-81 who
Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus) fed high fat diets
Ozorio R, et al.
Scientia Agricola, 62(3), 208-213 (2005)

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