D1756
地塞米松
≥98% (HPLC), powder, NOS induction inhibitor
别名:
(11β,16α)-9-氟-11,17,21-三羟基-16-甲基孕甾-1,4-二烯-3,20-二酮, 9α-氟-16α-甲基-11β,17α,21-三羟基-1,4-妊娠双烯-3,20-二酮, 9α-氟-16α-甲基泼尼松龙, 泼尼松龙F
About This Item
product name
地塞米松, ≥98% (HPLC), powder
质量水平
检测方案
≥98% (HPLC)
形式
powder
颜色
off-white
mp
262-264 °C (lit.)
溶解性
methanol: 25 mg/mL
创始人
Merck & Co., Inc., Kenilworth, NJ, U.S.
储存温度
2-8°C
SMILES字符串
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key
UREBDLICKHMUKA-CXSFZGCWSA-N
基因信息
human ... ABCB1(5243) , CYP3A4(1576) , IL4(3565) , IL5(3567) , NR3C1(2908)
mouse ... Abcb1a(18671) , Abcb1b(18669) , Ifng(15978) , Nos2(18126) , Ptgs2(19225) , Tnf(21926)
rat ... Ar(24208) , Nr3c1(24413) , Tnf(24835)
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一般描述
应用
- 诱导脂肪干细胞分化为成骨组织的培养基
- 用作脂肪细胞分化培养基的组分
- 体外刺激原代正常人支气管上皮细胞(NHBE)和气道平滑肌(ASM)。
生化/生理作用
特点和优势
包装
制备说明
重悬
警示用语：
Danger
危险声明
危险分类
Repr. 1B
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is Product D1756, Dexamethasone, soluble in?
Dexamethasone is practically insoluble in water. It is soluble in ethanol, methanol, acetone, dioxane, and slightly soluble in chloroform. Sigma routinely tests the solubility at 50 mg/mL in ethanol with heat, yielding a clear, colorless to faint yellow solution. However, dexamethasone will precipitate out of solution as the temperature returns to room temperature. At 25 mg/mL in methanol or ethanol, a clear colorless solution is obtained without heating. The solubility of dexamethasone in DMSO is 606 mg/mL at 25°C.
What is the solution stability of Product D1756, Dexamethasone?
Aqueous solutions of dexamethasone are stable for at least 30 days at 4°C. A stock solution at a concentration of 1mg/mL in absolute ethanol can be diluted 1:50 with sterile media and stored frozen as working aliquots.
Is Product D1756, Dexamethasone, suitable for cell culture?
This product has not been tested for cell culture. Please consider either Product No. D8893 or D4902, both of which are cell culture tested.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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