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表单
solid
旋光性
[α]22/D +99.2°, c = 0.90 in H2O(lit.)
颜色
white
溶解性
ethanol: 5 mg/mL
H2O: 800 mg/mL
SMILES字符串
Br.CO[C@H]1CC=C2CC[N@@H]3CCC4=C(CC(=O)OC4)[C@]23C1
InChI
1S/C16H21NO3.BrH/c1-19-13-3-2-12-5-7-17-6-4-11-10-20-15(18)8-14(11)16(12,17)9-13;/h2,13H,3-10H2,1H3;1H/t13-,16-;/m0./s1
InChI key
GFIGWAJEIMHJJB-LINSIKMZSA-N
基因信息
human ... CHRNA1(1134) , CHRNA10(57053) , CHRNA2(1135) , CHRNA3(1136) , CHRNA4(1137) , CHRNA5(1138) , CHRNA6(8973) , CHRNA7(1139) , CHRNA9(55584) , CHRNB1(1140) , CHRNB2(1141) , CHRNB3(1142) , CHRNB4(1143)
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生化/生理作用
Competitive nicotinic receptor antagonist.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
Y T Wang et al.
Neuroscience, 40(3), 759-767 (1991-01-01)
The purpose of this study was to determine if ambigual oesophageal motoneurons of the rat possess functional nicotinic cholinoceptors. In urethane anaesthetized rats, acetylcholine (20-50 pmol) delivered micropneumophoretically from multibarrelled pipettes to the compact formation of the nucleus ambiguus produced
C Rapier et al.
Journal of neurochemistry, 54(3), 937-945 (1990-03-01)
Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. We have compared the effects of a number of nicotinic agonists and antagonists on a perfused synaptosome preparation preloaded with [3H]dopamine. (-)-Nicotine, acetylcholine, and the nicotinic agonists
Sean H White et al.
Journal of neurophysiology, 112(2), 446-462 (2014-04-18)
Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholine activates an ionotropic receptor, which passes inward current to produce a
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