D149
Dihydro-β-erythroidine hydrobromide
solid
别名:
3β-1,6-Didehydro-14,17-dihydro-3-methoxy-16(15H)-oxaerythrinan-15-one hydrobromide
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选择尺寸
关于此项目
经验公式（希尔记法）:
C16H21NO3 · HBr
化学文摘社编号:
分子量:
356.25
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
form
solid
InChI
1S/C16H21NO3.BrH/c1-19-13-3-2-12-5-7-17-6-4-11-10-20-15(18)8-14(11)16(12,17)9-13;/h2,13H,3-10H2,1H3;1H/t13-,16-;/m0./s1
SMILES string
Br.CO[C@H]1CC=C2CC[N@@H]3CCC4=C(CC(=O)OC4)[C@]23C1
InChI key
GFIGWAJEIMHJJB-LINSIKMZSA-N
optical activity
[α]22/D +99.2°, c = 0.90 in H2O(lit.)
color
white
solubility
ethanol: 5 mg/mL, H2O: 800 mg/mL
Gene Information
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Biochem/physiol Actions
Competitive nicotinic receptor antagonist.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
C Rapier et al.
Journal of neurochemistry, 54(3), 937-945 (1990-03-01)
Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. We have compared the effects of a number of nicotinic agonists and antagonists on a perfused synaptosome preparation preloaded with [3H]dopamine. (-)-Nicotine, acetylcholine, and the nicotinic agonists
Y T Wang et al.
Neuroscience, 40(3), 759-767 (1991-01-01)
The purpose of this study was to determine if ambigual oesophageal motoneurons of the rat possess functional nicotinic cholinoceptors. In urethane anaesthetized rats, acetylcholine (20-50 pmol) delivered micropneumophoretically from multibarrelled pipettes to the compact formation of the nucleus ambiguus produced
Sean H White et al.
Journal of neurophysiology, 112(2), 446-462 (2014-04-18)
Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholine activates an ionotropic receptor, which passes inward current to produce a
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