所有图片(2)
About This Item
经验公式（希尔记法）:
C17H23NO · C4H6O6
CAS号:
分子量:
407.46
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32
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表单
powder
颜色
white
溶解性
H2O: >10 mg/mL
SMILES字符串
O[C@@H]([C@H](O)C(O)=O)C(O)=O.CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc4ccc(O)cc34
InChI
1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;1-,2-/m10/s1
InChI key
RWTWIZDKEIWLKQ-FEBOIHDFSA-N
基因信息
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
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应用
Dextrorphan tartrate has been used to study its effects on blood glucose levels by targeting pancreatic islets.
生化/生理作用
Dextrorphan is a noncompetitive NMDA glutamate receptor antagonist that attenuates glutamate neurotoxicity in cortical cell cultures.
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
A I Faden et al.
Science (New York, N.Y.), 244(4906), 798-800 (1989-05-19)
Brain injury induced by fluid percussion in rats caused a marked elevation in extracellular glutamate and aspartate adjacent to the trauma site. This increase in excitatory amino acids was related to the severity of the injury and was associated with
Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets
Okka S, et al.
Cell Chemical Biology (2021)
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