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Merck
CN

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

别名:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
物种:
UniProtKB ID:
基因ID:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

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Small Molecule - Agonist

货号
说明
物种
Reversin 205, ≥98% (HPLC), film,
物种
mouse, rat, human
N-甲基- D -天冬氨酸, ≥98% (TLC), solid,
物种
human, rat
(S)-AMPA, ≥98%,
物种
mouse, human, rat
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human

Small Molecule - Allosteric Modulator

货号
说明
物种
阿坎酸钙, ≥98% (HPLC), powder,
物种
human
阿坎酸钙, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
物种
human
阿坎酸钙, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
DL-2-氨基己二酸, ≥99%,
物种
rat
2-苯基喹啉, 99%,
物种
rat
Ro 25-6981 盐酸盐 水合物, ≥98% (HPLC), powder,
物种
human
Ro 8-4304, solid,
物种
human
精胺, ≥97%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
PhosphoDetect Anti-NMDA NR2B (pTyr¹⁴⁷²) Rabbit pAb, liquid, Calbiochem®,
物种反应性
rat
应用
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-NMDAR2B Antibody, clone 5C18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, canine, feline, monkey, mouse, rat
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-GRIN2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot

Small Molecule - Blocker

货号
说明
物种
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物种
human
胍丁胺 硫酸盐, ≥97%, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
喷他脒 羟乙基磺酸盐, powder,
物种
human
奥芬那君 盐酸盐, ≥98.0% (AT),
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRIN2B,
物种
human
MISSION® esiRNA, targeting mouse Grin2b,
物种
mouse