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Merck
CN

K1884

Sigma-Aldrich

S-(+)-Ketamine hydrochloride

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经验公式(希尔记法):
C13H16ClNO · HCl
CAS号:
分子量:
274.19
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.77

形式

powder

质量水平

药品控制

USDEA Schedule III; stupéfiant (France); regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain)

储存温度

2-8°C

SMILES字符串

Cl.CN[C@@]1(CCCCC1=O)c2ccccc2Cl

InChI

1S/C13H16ClNO.ClH/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14;/h2-3,6-7,15H,4-5,8-9H2,1H3;1H/t13-;/m0./s1

InChI key

VCMGMSHEPQENPE-ZOWNYOTGSA-N

生化/生理作用

Selective NMDA glutamate receptor antagonist.

象形图

Health hazardExclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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PloS one, 8(12), e81320-e81320 (2013-12-19)
To promote cancer research and to develop innovative therapies, refined pre-clinical mouse tumor models that mimic the actual disease in humans are of dire need. A number of neoplasms along the B cell lineage are commonly initiated by a translocation
Adam L Halberstadt et al.
Psychopharmacology, 233(7), 1215-1225 (2016-01-14)
Methoxetamine (MXE) is a ketamine analog sold online that has been subject to widespread abuse for its dissociative and hallucinogenic effects. Previous studies have shown that MXE has high affinity for the phencyclidine (PCP) binding site located within the channel
M Nishimura et al.
Neuroscience letters, 274(2), 131-134 (1999-12-20)
Ketamine is usually administered as a racemate, which is composed of the two isomers, S(+)-and R(-)-ketamine. Recently, we have shown that racemic ketamine at clinical relevant concentrations specifically inhibits the transporter proteins for norepinephrine, dopamine and serotonin heterologously expressed in
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PloS one, 8(9), e75737-e75737 (2013-10-08)
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Kallol Bera et al.
Frontiers in cellular neuroscience, 13, 499-499 (2019-12-05)
The target for the "rapid" (<24 h) antidepressant effects of S-ketamine is unknown, vitiating programs to rationally develop more effective rapid antidepressants. To describe a drug's target, one must first understand the compartments entered by the drug, at all levels-the

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