product name
N , N -二甲基甘氨酸, ≥99%
质量水平
检测方案
≥99%
形式
powder
技术
ligand binding assay: suitable
颜色
white to off-white
mp
178-182 °C (lit.)
应用
peptide synthesis
SMILES字符串
CN(C)CC(O)=O
InChI
1S/C4H9NO2/c1-5(2)3-4(6)7/h3H2,1-2H3,(H,6,7)
InChI key
FFDGPVCHZBVARC-UHFFFAOYSA-N
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生化/生理作用
N,N-二甲基甘氨酸 (DMG) 是一种天然 N-甲基化甘氨酸，用于与其他 N-甲基化甘氨酸（如肌氨酸和 β信息。N，N-二甲基甘氨酸用于开发基于甘氨酸的离子液体和乳化剂。N,N-二甲基甘氨酸作为 COPD 患者蛋白质降解的生物标志物可能有用。DMG 被用作识别、区分和表征氨基酸甲基转移酶的底物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
B A Binzak et al.
American journal of human genetics, 68(4), 839-847 (2001-03-07)
Dimethylglycine dehydrogenase (DMGDH) (E.C. number 1.5.99.2) is a mitochondrial matrix enzyme involved in the metabolism of choline, converting dimethylglycine to sarcosine. Sarcosine is then transformed to glycine by sarcosine dehydrogenase (E.C. number 1.5.99.1). Both enzymes use flavin adenine dinucleotide and
S H Moolenaar et al.
Clinical chemistry, 45(4), 459-464 (1999-04-02)
A38-year-old man presented with a history of fish odor (since age 5) and unusual muscle fatigue with increased serum creatine kinase. Our aim was to identify the metabolic error in this new condition. We used 1H NMR spectroscopy to study
Jian Yan et al.
The American journal of clinical nutrition, 95(5), 1060-1071 (2012-03-16)
In 1998 choline Adequate Intakes of 425 and 450 mg/d were established for nonpregnant and pregnant women, respectively. However, to our knowledge, no dose-response studies have been conducted to evaluate the effects of pregnancy or maternal choline intake on biomarkers
Sheila M Innis et al.
The American journal of clinical nutrition, 93(3), 564-568 (2011-01-14)
Choline is an important constituent of acetylcholine. Choline is needed for acetylcholine in the nonneuronal acetylcholine system that includes epithelial cells of the lung and intestine, endothelial cells, and immune cells. Plasma free choline concentrations are low in children with
Baljit K Ubhi et al.
The European respiratory journal, 40(2), 345-355 (2011-12-21)
There is a paucity of biomarkers for chronic obstructive pulmonary disease (COPD). Metabolomics were applied to a defined COPD patient cohort from the ECLIPSE study (Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points). Results were correlated with accepted biomarkers
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