推荐产品
生物来源
yeast
质量水平
检测方案
≥95%
形式
powder
储存温度
−20°C
SMILES字符串
[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O
InChI
1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;
InChI key
MAGSIBHRUIBONY-UHFFFAOYSA-N
相关类别
一般描述
胞苷5′-二磷酸酯（CDP）是在尿苷酸激酶（UMPK）的催化下通过胞苷单磷酸酯（CMP）尿苷单磷酸酯（UMP）的磷酰基转移而合成的。CTP合成酶催化CTP转化为CDP中间体（如CDP-二酰基甘油、CDP-胆碱和CDP-乙醇胺）的反应，进行磷脂的生物合成。
应用
胞苷5′-二磷酸钠盐水合物已被用于：
- 作为底物用于金鱼眼切片的核苷二磷酸酶 (NDPase) 组织化学测定
- 核糖核苷酸还原酶测定
- dCDP形成测定
生化/生理作用
胞苷 5′-二磷酸 (CDP) 可用作 CDP（二磷酸核苷）激酶 的底物，生成支持DNA和 RNA 生物合成的 CTP，以及生成 dCMP 的核糖核苷酸还原酶。
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Yan Zhang et al.
Biochemistry, 50(25), 5615-5623 (2011-05-13)
Bacillus subtilis class Ib ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides, providing the building blocks for DNA replication and repair. It is composed of two proteins: α (NrdE) and β (NrdF). β contains the metallo-cofactor, essential for
Microglial cells in the retina of Carassius auratus: effects of optic nerve crush
Salvador-Silva M, et al.
The Journal of Comparative Neurology, 417(4), 431-447 (2000)
Ribonucleotide reductase requires subunit switching in hypoxia to maintain DNA replication
Foskolou IP, et al.
Molecular Cell, 66(2), 206-220 (2017)
CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae
Chang YF and Carman GM
Progress in Lipid Research, 47(5), 333-339 (2008)
Purine and pyrimidine nucleotide synthesis and metabolism
The Arabidopsis Book / American Society of Plant Biologists, 1 (2002)
实验方案
ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
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