所有图片(3)
别名:
5-胆甾烯-3β-醇硫酸盐 钠盐, 胆固醇 3-硫酸盐 钠盐, 胆固醇硫酸酯 钠盐, 胆固醇硫酸钠
经验公式（希尔记法）:
C27H45NaO4S
CAS号:
分子量:
488.70
Beilstein:
3899884
MDL编号:
UNSPSC代码:
41141804
eCl@ss:
39023139
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
生物来源
synthetic
质量水平
描述
anionic
检测方案
≥98% (TLC)
形式
powder
运输
ambient
储存温度
−20°C
SMILES字符串
[H][C@@]([C@H](C)CCCC(C)C)([C@@]1(C)CC[C@@]23[H])CC[C@]1([C@](CC=C4C[C@H](CC[C@]34C)OS([O-])(=O)=O)2[H])[H].[Na+]
InChI
1S/C27H46O4S.Na/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(31-32(28,29)30)13-15-26(20,4)25(22)14-16-27(23,24)5;/h9,18-19,21-25H,6-8,10-17H2,1-5H3,(H,28,29,30);/q;+1/p-1/t19-,21+,22+,23-,24+,25+,26+,27-;/m1./s1
InChI key
LMPVQXVJTZWENW-KPNWGBFJSA-M
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应用
利用胆甾醇硫酸钠作为胆固醇的来源制备埃德加试剂的生长培养基，用于胚胎学实验。以其作为薄层色谱法分离人体角质层脂质的标准品。
生化/生理作用
胆固醇硫酸酯是人类精子的天然成分，在精子的成熟过程中起着重要角色。它也可能参与精子的获能并使卵子穿透。低浓度的硫酸胆固醇可抑制顶体酶，顶体酶是精子顶体中的一种蛋白酶，可促进卵子穿透。
制备说明
胆固醇硫酸钠在 10 mg/mL 氯仿-甲醇 (1:1) 混合液中生成澄清、无色溶液。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
N Y Schürer et al.
Experimental dermatology, 4(1), 46-51 (1995-02-01)
There is a need in many studies on the epidermal permeability barrier for practical and reliable separation of all major fractions of human stratum corneum lipids. Various methods have been described including thin layer chromatography, high performance thin layer chromatography
J Langlais et al.
Proceedings of the National Academy of Sciences of the United States of America, 78(12), 7266-7270 (1981-12-01)
Cholesteryl sulfate is a normal constituent of human spermatozoa. The in vitro uptake of tritiated cholesteryl sulfate resulted in the labeling of all spermatozoa as demonstrated by light-microscope radioautography. The binding of the sterol sulfate was localized mainly in the
Lois G Edgar et al.
Methods in cell biology, 107, 151-175 (2012-01-10)
The direct manipulation of embryonic cells is an important tool for addressing key questions in cell and developmental biology. C. elegans is relatively unique among genetic model systems in being amenable to manipulation of embryonic cells. Embryonic cell manipulation has
Gelen Rodríguez et al.
Physical chemistry chemical physics : PCCP, 14(42), 14523-14533 (2012-09-27)
Bicellar systems are a fascinating category of versatile lipid assemblies that comprise bilayered disk-shaped nanoaggregates formed in water by long and short alkyl chain phospholipids. Bicelles bridge the gap between micelles and lipid vesicles by combining the attractive properties of
Tingting Guan et al.
International journal of pharmaceutics, 410(1-2), 180-187 (2011-03-19)
The main purpose of this study was to prepare nimodipine-loaded nanoliposomes for injection and evaluate their characteristics after lyophilization. Nimodipine-loaded nanoliposomes were prepared by the emulsion-ultrasonic method with sodium cholesterol sulfate (SCS) as the regulator and then lyophilized by adding
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