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Merck
CN

C9026

Sigma-Aldrich

雨蛙素

≥95% (HPLC), suitable for immunohistochemistry

别名:

[Tyr(SO3H)4]雨蛙素, pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2, 硫酸化蓝肽, 蓝肽, 雨蛙肽

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About This Item

经验公式(希尔记法):
C58H73N13O21S2
CAS号:
分子量:
1352.40
Beilstein:
5422487
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

product name

雨蛙素, ≥95% (HPLC)

质量水平

检测方案

≥95% (HPLC)

形式

powder

技术

immunohistochemistry: suitable

颜色

white

储存温度

−20°C

SMILES字符串

CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CNC(=O)C(NC(=O)[C@H](Cc3ccc(OS(O)(=O)=O)cc3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]4CCC(=O)N4)[C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc5ccccc5)C(N)=O

InChI

1S/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)92-94(89,90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,36+,37+,38+,39+,40+,41+,42+,43+,49?/m1/s1

InChI key

YRALAIOMGQZKOW-HJMGKOKZSA-N

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相关类别

Amino Acid Sequence

Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2

应用

蛙皮素可用于诱导Sprague-Dawley大鼠、小鼠和其他实验动物产生胰腺炎。

生化/生理作用

对疼痛感知的影响是相互矛盾的。它可以预防胆囊疼痛、肾绞痛和间歇性跛行疼痛;然而,一般来说,它是内源性阿片类药物的拮抗剂。
蛙皮素是一种胃调节分子,其作用类似于胆囊收缩素。它有一个硫酸酪氨酸残基,可诱导平滑肌收缩。它具有胃泌素样活性。蛙皮素可用于研究由NF-κB上调细胞间黏附分子1(ICAM-1)和炎症相关分子(如NADPH氧化酶和Janus激酶信号转导蛋白)等蛋白介导的细胞信号传导。蛙皮素还调控体温调节、镇静和饱腹感。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. How do I store solutions of Product C9026, Caerulein?

    Solutions can be frozen at pH>7 for a least a week, and may be good for several months.    

  6. What is Product C9026, Caerulein, soluble in?

    It is soluble in 50 mM ammonium hydroxide at a concentration of 1 mg/mL. Note that this is information from analytical testing, and is not application based.

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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