C7629
L-瓜氨酸
≥98% (TLC)
别名:
L-2-氨基-5-脲基戊酸, （S）-2-氨基-5-脲基戊酸
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关于此项目
经验公式（希尔记法）:
C6H13N3O3
化学文摘社编号:
分子量:
175.19
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
206-759-6
MDL number:
Beilstein/REAXYS Number:
1725416
产品名称
L-瓜氨酸, ≥98% (TLC)
InChI key
RHGKLRLOHDJJDR-BYPYZUCNSA-N
InChI
1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
SMILES string
N[C@@H](CCCNC(N)=O)C(O)=O
assay
≥98% (TLC)
form
powder
color
white to off-white
application(s)
detection
Quality Level
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Application
L-瓜氨酸已用于超高效液相色谱中，以验证参与变质过程协调的代谢物。
Biochem/physiol Actions
人们发现，口服L-瓜氨酸可改善人类镰状细胞疾病的状况。在NO（一氧化氮）合成酶缺陷的情况下，可以服用L-瓜氨酸，替代L-精氨酸。人们发现，L-瓜氨酸补充剂能满足NO（一氧化氮）依赖型信号传导的目的。
通过NO（一氧化氮）合成酶，从L-精氨酸生产一氧化氮的中间体。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Schwedhelm E
British Journal of Clinical Pharmacology, 65(1), 51-59 (2008)
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Hayashi T
Proceedings of the National Academy of Sciences of the USA null
Nu-Hydroxy-L-arginine Is an Intermediate in the Biosynthesis of Nitric Oxide from L-Arginin
Dennis J. Stuehr
The Journal of Biological Chemistry, 266, 6259-6263 (1991)
Metabolomic insights into system-wide coordination of vertebrate metamorphosis.
Ichu TA
BMC Developmental Biology, 14:5, 1-24 (2014)
Ran Lin et al.
Molecular cell, 68(1), 198-209 (2017-10-07)
In addition to responding to environmental entrainment with diurnal variation, metabolism is also tightly controlled by cell-autonomous circadian clock. Extensive studies have revealed key roles of transcription in circadian control. Post-transcriptional regulation for the rhythmic gating of metabolic enzymes remains
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