推荐产品
生物来源
(Ovotestis from sea hare)
质量水平
方案
≥90% (HPLC)
表单
lyophilized powder
储存温度
−20°C
SMILES字符串
O[C@H]1[C@@H](O)[C@H]2O[C@@H]1COP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)[n@H]4cnc5C(=N)[N@@H]2C=Nc45
InChI
1S/C15H21N5O13P2/c16-12-7-13-18-4-19(12)14-10(23)8(21)5(31-14)1-29-34(25,26)33-35(27,28)30-2-6-9(22)11(24)15(32-6)20(13)3-17-7/h3-6,8-11,14-16,21-24H,1-2H2,(H,25,26)(H,27,28)/t5-,6-,8-,9-,10-,11-,14-,15-/m1/s1
InChI key
BQOHYSXSASDCEA-KEOHHSTQSA-N
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相关类别
应用
环状二磷酸腺苷核糖已被用于刺激星形胶质细胞激活 CD38 信号。它也被用于缓冲蛋白胨水的补充，以恢复肠炎链球菌。
环腺苷二磷酸核糖（cADPR）是细胞内第二信使，其通过兰尼碱受体调动细胞内 Ca2+ 从肌质网中释放。CADPR 也是葡萄糖诱导内分泌胰腺释放胰岛素以及植物中脱落酸诱导的钙释放的第二信使。
生化/生理作用
调动细胞内 Ca2+；调节由兰尼碱特异性阻断的 Ca2+诱导的 Ca2+ 释放；葡萄糖诱导胰岛素从内分泌胰腺释放以及植物中脱落酸诱导钙释放的第二信使。
包装
根据核苷酸含量确定包装尺寸。
外形
冻干粉末
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Shunichi Kajioka et al.
The Journal of urology, 186(2), 736-744 (2011-06-21)
To clarify the properties of adenosine triphosphate sensitive K+ channel in human detrusor smooth muscle we examined the effect of the representative nicotinic acid derivatives β-nicotinamide adenine dinucleotide, cyclic adenosine diphosphate ribose and nicotinic acid adenine dinucleotide phosphate (Sigma-Aldrich®) on
Effects of carob bean gum on performance, nutrient digestibility and Salmonella enterica var. Enteritidis colonisation in chickens
Vila B, et al.
Food Research International, 45(2), 1133-1138 (2012)
Hon Cheung Lee
Science China. Life sciences, 54(8), 699-711 (2011-07-26)
The concept advanced by Berridge and colleagues that intracellular Ca(2+)-stores can be mobilized in an agonist-dependent and messenger (IP(3))-mediated manner has put Ca(2+)-mobilization at the center stage of signal transduction mechanisms. During the late 1980s, we showed that Ca(2+)-stores can
Tom Snelling et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(50), e2313148120-e2313148120 (2023-12-07)
The atypical protein kinase ALPK1 is activated by the bacterial nucleotide sugar ADP-heptose and phosphorylates TIFA to switch on a signaling pathway that combats microbial infection. In contrast, ALPK1 mutations cause two human diseases: the ALPK1[T237M] and ALPK1[Y254C] mutations underlie
S Takasawa et al.
Science (New York, N.Y.), 259(5093), 370-373 (1993-01-15)
Inositol 1,4,5-trisphosphate (IP3) is thought to be a second messenger for intracellular calcium mobilization. However, in a cell-free system of islet microsomes, cyclic adenosine diphosphate-ribose (cADP-ribose), a nicotinamide adenine dinucleotide (NAD+) metabolite, but not IP3, induced calcium release. In digitonin-permeabilized
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