C5041
6-羧基荧光素二乙酸酯
~95% purity (HPLC), powder
别名:
6-CFDA, 6-羧基-二-氧-乙酰荧光素
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关于此项目
经验公式（希尔记法）:
C25H16O9
化学文摘社编号:
分子量:
460.39
Beilstein:
67043
MDL编号:
UNSPSC代码:
12171500
PubChem化学物质编号:
NACRES:
NA.47
产品名称
6-羧基荧光素二乙酸酯, ≥95% (HPLC)
方案
≥95% (HPLC)
表单
powder
颜色
white to yellow
溶解性
chloroform/ethanol (1:1): 9.80-10.20 mg/mL, clear, colorless to light yellow
应用
diagnostic assay manufacturing
hematology
histology
储存温度
−20°C
SMILES字符串
CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C24OC(=O)c5ccc(cc45)C(O)=O)c1
InChI
1S/C25H16O9/c1-12(26)31-15-4-7-18-21(10-15)33-22-11-16(32-13(2)27)5-8-19(22)25(18)20-9-14(23(28)29)3-6-17(20)24(30)34-25/h3-11H,1-2H3,(H,28,29)
InChI key
QMOGCCYGOPYYNT-UHFFFAOYSA-N
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应用
6-羧基荧光素二乙酸酯已用于区分活细胞和凋亡细胞。 非凋亡的活细胞聚集 6-羧基荧光素，但不聚集膜联蛋白。
荧光波长 λex 492 nm；λem 517 nm 溶于 0.1M Tris，pH 8.0。
荧光波长 λex 492 nm；λem 517 nm 溶于 0.1M Tris，pH 8.0。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
M Kawai et al.
Journal of applied microbiology, 86(3), 496-504 (1999-04-10)
Physiologically active bacteria in purified water used in the manufacturing process of pharmaceutical products were enumerated in situ. Bacteria with growth potential were enumerated using the micro-colony technique and direct viable counting (DVC), followed by 24 h of incubation in
Sung-Uk Lee et al.
PloS one, 14(3), e0214253-e0214253 (2019-03-27)
N-acetylglucosamine (GlcNAc) branching of Asn (N)-linked glycans inhibits pro-inflammatory T cell responses and models of autoimmune diseases such as Multiple Sclerosis (MS). Metabolism controls N-glycan branching in T cells by regulating de novo hexosamine pathway biosynthesis of UDP-GlcNAc, the donor
Yeli Gong et al.
PloS one, 7(10), e47435-e47435 (2012-10-19)
The MOG35-55 peptide-induced experimental autoimmune encephalomyelitis (EAE) model in C57BL/6 mice is a useful animal model to explore therapeutic approaches to T cell-mediated autoimmune diseases because the dominant T-cell epitope(s) have been defined. It is rational that antigen-specific immunosuppression can
Yuan Liu et al.
Journal of biomedical optics, 12(1), 014014-014014 (2007-03-09)
Intravital imaging of hepatobiliary excretion is vital for elucidating liver metabolism. In this work, we describe a novel method to observe the intravital dynamics of the uptake, processing, and excretion of an organic anion, 6-carboxyfluorescein diacetate (6-CFDA) in the hepatobiliary
Garry R Smith et al.
Journal of molecular neuroscience : MN, 52(3), 446-458 (2013-11-28)
Severe seizure activity is associated with reoccurring cycles of excitotoxicity and oxidative stress that result in progressive neuronal damage and death. Intervention with these pathological processes is a compelling disease-modifying strategy for the treatment of seizure disorders. We have optimized
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