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Merck
CN

C4375

Sigma-Aldrich

N-氨基甲酰-L-谷氨酸

≥98.0% (TLC)

别名:

N-(aminocarbonyl)-L-glutamic acid

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About This Item

经验公式(希尔记法):
C6H10N2O5
CAS号:
分子量:
190.15
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26

产品名称

N-氨基甲酰-L-谷氨酸,

方案

≥98.0% (TLC)

质量水平

表单

powder

颜色

white

应用

cell analysis

储存温度

2-8°C

SMILES字符串

NC(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1

InChI key

LCQLHJZYVOQKHU-VKHMYHEASA-N

基因信息

human ... CPS1(1373)

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生化/生理作用

N-氨基甲酰-L-谷氨酸(氨甲酰谷氨酸)被用于研究其作为替代疗法对N-乙酰谷氨酸合成酶(NAGS)缺乏症的治疗潜力,并用于治疗高氨血症。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xin Wu et al.
Amino acids, 39(3), 831-839 (2010-03-10)
This study determined effects of dietary supplementation with L-arginine (Arg) or N-carbamylglutamate (NCG) on intestinal health and growth in early-weaned pigs. Eighty-four Landrace x Yorkshire pigs (average body weight of 5.56+/-0.07 kg; weaned at 21 days of age) were fed
Luca Filippi et al.
Neonatology, 97(3), 286-290 (2009-11-06)
In propionic aciduria and methylmalonic aciduria, hyperammonemia as a symptom of metabolic decompensation is one of the major clinical problems. Hyperammonemia is a true neonatal emergency with high mortality and neurological complications in most survivors. It requires a rapid and
Sema Kalkan Ucar et al.
Metabolic brain disease, 24(3), 409-414 (2009-08-19)
Maple syrup urine disease (MSUD) is a defect in the catabolism of the branched-chain amino acids; leucine, isoleucine, and valine. Affected patients may also develop hyperammonaemia of unknown etiology. This report describes a four-year-old girl with MSUD, who presented with
Nicholas Ah Mew et al.
Pediatrics, 126(1), e208-e214 (2010-06-23)
The objective of this study was to determine whether N-carbamylglutamate (NCG) reduces plasma levels of ammonia and glutamine and increases the rate of ureagenesis in patients with propionic acidemia (PA). Identical 4-hour studies were performed before and immediately after a
Ljubica Caldovic et al.
The Journal of pediatrics, 145(4), 552-554 (2004-10-14)
In a patient with N-acetylglutamate synthase (NAGS) deficiency, incorporation of an isotopic label from ammonium chloride into urea was markedly reduced before treatment with N-carbamyl-L-glutamate (NCLG) and completely normalized following treatment. Blood ammonia rose following ammonium tracer ingestion before treatment

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