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Merck
CN

C3633

Sigma-Aldrich

DL-胱硫醚

≥90% (HPLC)

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别名:
半胱氨酸, S-(2-氨基-2-甲酸基乙基)高半胱氨酸
线性分子式:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
CAS号:
分子量:
222.26
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.26

质量水平

检测方案

≥90% (HPLC)

形式

powder

颜色

white to off-white

mp

281 °C (dec.)

储存温度

2-8°C

SMILES字符串

NC(CCSCC(N)C(O)=O)C(O)=O

InChI

1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)

InChI key

ILRYLPWNYFXEMH-UHFFFAOYSA-N

基因信息

human ... BHMT(635)

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生化/生理作用

胱硫醚是氨基酸半胱氨酸生物合成的一种中间体。胱硫醚可作为底物用于区分和分析胱硫醚γ-裂合酶。

其他说明

4种立体异构体的混合物;L-, D-, L-allo-和D-allo-胱硫醚。

制备说明

由Stekol法制备。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Oxidative stress is thought to account for aberrant redox homeostasis and contribute to aging and disease. However, more often than not, administration of antioxidants is ineffective, suggesting that our current understanding of the underlying regulatory processes is incomplete. Recent Advances:
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International journal of molecular sciences, 20(4) (2019-02-20)
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the metabolism of the essential amino acid methionine. Hcy is considered a risk factor for atherosclerosis and cardiovascular disease (CVD), but the molecular basis of these associations remains elusive. The
Shuai Yuan et al.
Antioxidants & redox signaling, 27(10), 634-653 (2017-04-12)
Hydrogen sulfide (H In light of the recent understanding of oxidized sulfide metabolite formation and reactivity, comparatively few studies have been reported comparing cellular biological and in vivo effects of H Additional studies regarding persulfide and polysulfide formation and molecular
Qinghai Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(6), 2200-2213 (2018-09-27)
The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular endothelial cell dysfunction. Hydrogen sulfide (H2S) has been shown to have an anti-oxidative effect, but its mode
Xu Cao et al.
Antioxidants & redox signaling, 31(1), 1-38 (2018-05-24)
Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous transmitter alongside nitric oxide and carbon monoxide. In

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