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Merck
CN

C3411

Sigma-Aldrich

2′,7′-双(2-羧乙基)-5(6)-羧基荧光素

≥90% (HPLC)

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别名:
BCECF
经验公式(希尔记法):
C27H20O11
CAS号:
分子量:
520.44
Beilstein:
8375770
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥90% (HPLC)

形式

powder

储存温度

−20°C

SMILES字符串

OC(=O)CCc1cc2c(OC3=CC(=O)C(CCC(O)=O)=CC3=C2c4cc(ccc4C(O)=O)C(O)=O)cc1O

InChI

1S/C27H20O11/c28-19-10-21-17(7-12(19)2-5-23(30)31)25(16-9-14(26(34)35)1-4-15(16)27(36)37)18-8-13(3-6-24(32)33)20(29)11-22(18)38-21/h1,4,7-11,28H,2-3,5-6H2,(H,30,31)(H,32,33)(H,34,35)(H,36,37)

InChI key

DKROGDOAOXDINY-UHFFFAOYSA-N

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应用

2′,7′-双(2-羧乙基)-5(6)-羧基荧光素已被用于荧光筛选测定中,以确定pH。

生化/生理作用

2′,7′-双(2-羧乙基)-5(6)-羧基荧光素(BCECF) 可用于研究多药耐药相关蛋白(MRP)转运蛋白在细胞内的作用。已知BCECF会干扰药物外排相互作用。
用于测量淋巴细胞中细胞质pH值的荧光指示剂。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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