推荐产品
产品名称
L-刀豆氨酸, ≥98% (TLC), powder, from Canavalia ensiformis
生物来源
Canavalia ensiformis
质量水平
方案
≥98% (TLC)
表单
powder
颜色
white to yellow
溶解性
H2O: <100 mg/mL
应用
detection
储存温度
2-8°C
SMILES字符串
N[C@@H](CCONC(N)=N)C(O)=O
InChI
1S/C5H12N4O3/c6-3(4(10)11)1-2-12-9-5(7)8/h3H,1-2,6H2,(H,10,11)(H4,7,8,9)/t3-/m0/s1
InChI key
FSBIGDSBMBYOPN-VKHMYHEASA-N
相关类别
生化/生理作用
一种天然存在的 L -氨基酸,由于其结构相似性而干扰 L -精氨酸利用酶。它是诱导型一氧化氮合酶 (iNOS) 的选择性抑制剂。iNOS 产生过量的 NO 在脓毒性休克和慢性炎症的病理生理过程中起角色至关重要的作用。
刀豆氨酸是一种天然存在的 L-氨基酸,由于其结构相似性,可干扰 L-精氨酸利用酶。它是诱导型一氧化氮合酶 (iNOS) 的选择性抑制剂。iNOS 产生过量的 NO 在脓毒性休克和慢性炎症的病理生理过程中起角色至关重要的作用。
警示用语:
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
The Journal of biological chemistry, 288(7), 5166-5175 (2012-12-25)
Transport along the endolysosomal system requires multiple fusion events at early and late endosomes. Deletion of several endosomal fusion factors, including the Vac1 tether and the Class C core vacuole/endosome tethering (CORVET) complex-specific subunits Vps3 and Vps8, results in a
International journal of cancer, 130(9), 2164-2175 (2011-06-08)
Single amino acid arginine deprivation is a promising strategy in modern metabolic anticancer therapy. Its potency to inhibit tumor growth warrants the search for rational chemo- and radio-therapeutic approaches to be co-applied. In this report, we evaluated, for the first
Nature communications, 10(1), 439-439 (2019-01-27)
RNA-guided nucleases of the CRISPR/Cas type can be repurposed as programmable nucleotide deaminases to mediate targeted nucleotide substitutions. Such base editors have enormous potential in genome editing, gene therapy and precision breeding. However, current editors suffer from limited specificity in
The international journal of biochemistry & cell biology, 65, 268-274 (2015-06-29)
Impairment of mitochondrial protein homeostasis disrupts mitochondrial function and causes human diseases and aging, but the molecular mechanisms of protein synthesis and quality control in mammalian mitochondria are not fully understood. Here we demonstrate in human cells that misincorporation of
BMC biology, 9, 70-70 (2011-10-26)
The uptake of drugs into cells has traditionally been considered to be predominantly via passive diffusion through the bilayer portion of the cell membrane. The recent recognition that drug uptake is mostly carrier-mediated raises the question of which drugs use
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