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Merck
CN

C1131

胞苷 5′-一磷酸

≥99% (HPLC), synthetic, powder

别名:

5′-CMP, 5′-胞苷酸, C-5′-P

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关于此项目

经验公式（希尔记法）:
C9H14N3O8P
化学文摘社编号:
63-37-6
分子量:
323.20
NACRES:
NA.51
PubChem Substance ID:
24892358
UNSPSC Code:
41106305
EC Number:
200-556-6
MDL number:
MFCD00006544
Beilstein/REAXYS Number:
46982
Assay:
≥99% (HPLC)
Biological source:
synthetic
Form:
powder
Solubility:
1 M NH4OH: 50 mg/mL, clear, colorless
Storage temp.:
2-8°C

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产品名称

胞苷 5′-一磷酸, Sigma Grade, ≥99% (HPLC), synthetic, powder

InChI key

IERHLVCPSMICTF-XVFCMESISA-N

InChI

1S/C9H14N3O8P/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O

biological source

synthetic

grade

Sigma Grade

assay

≥99% (HPLC)

form

powder

solubility

1 M NH4OH: 50 mg/mL, clear, colorless

storage temp.

2-8°C

Quality Level

200

相关类别

Application

胞苷5′-单磷酸已用于拉曼光谱研究。

Biochem/physiol Actions

核苷二磷酸胞苷二磷酸(CDP)和尿苷二磷酸(UDP)是合成嘧啶的必需组分胞苷5′-单磷酸(CMP)核苷酸用于仿生磷灰石的吸附研究，用于模拟骨骼矿物质。它也可用作儿科制剂中的免疫增强剂。
胞苷5′-单磷酸 (CMP) 作为单磷酸尿苷 (UMP)/单磷酸胞苷 (CMP) 激酶（酶代码 EC 2.7.4.4）的底物形成 CDP，CDP 经磷酸化形成 CTP，支持 DNA 和 RNA 的生物合成。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000519723
0000519723
0000509982
0000509987
0000509982

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Linda J Reha-Krantz et al.
Biochemistry, 50(46), 10136-10149 (2011-10-26)
The adenine base analogue 2-aminopurine (2AP) is a potent base substitution mutagen in prokaryotes because of its enhanceed ability to form a mutagenic base pair with an incoming dCTP. Despite more than 50 years of research, the structure of the
A Hirono et al.
Clinica chimica acta; international journal of clinical chemistry, 130(2), 189-197 (1983-05-30)
Three new variants of pyrimidine 5'-nucleotidase (P5N) found in Japan were studied. They are characterized by slow electrophoretic mobility and a high Michaelis constant for cytidine 5'-monophosphate as has been described in previously reported cases, but are unique with respect
Páraic M Keane et al.
Physical chemistry chemical physics : PCCP, 14(18), 6307-6311 (2012-02-24)
The decay pathways of UV-excited cytosine polymers are investigated using picosecond time-resolved infrared spectroscopy. Similar yields of a non-emissive (1)nπ* state are found in the single-stranded dC(30) polymer as in the dCMP monomer, but with a longer lifetime in the
Otto Geiger et al.
Biochimica et biophysica acta, 1831(3), 503-513 (2012-08-28)
Phosphatidylcholine (PC) is the major membrane-forming phospholipid in eukaryotes and is estimated to be present in about 15% of the domain Bacteria. Usually, PC can be synthesized in bacteria by either of two pathways, the phospholipid N-methylation (Pmt) pathway or
An enzymatic alternative for the synthesis of nucleoside 5?-monophosphates
Gudino ED, et al.
Enzyme and Microbial Technology, 111, 1-6 (2018)
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实验方案

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.

LC/MS Analysis of Nucleotides SeQuant® ZIC®-cHILIC – Effect of pH

ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.

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