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Merck
CN

C1006

胞苷5′-单磷酸 二钠盐

≥99%, synthetic, crystalline

别名:

C-5′-P, CMP

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关于此项目

线性分子式:
C9H12N3O8PNa2
化学文摘社编号:
分子量:
367.16
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
229-819-3
MDL number:
Assay:
≥99%
Biological source:
synthetic
Form:
crystalline
Solubility:
water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
Storage temp.:
2-8°C
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产品名称

胞苷5′-单磷酸 二钠盐, Sigma Grade, ≥99%, crystalline

InChI key

RCIPNLSOCXMZDD-UHFFFAOYSA-N

InChI

1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;

SMILES string

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O

biological source

synthetic

grade

Sigma Grade

assay

≥99%

form

crystalline

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

2-8°C

Quality Level

Application

胞苷5′-单磷酸二钠盐已用于:
  • 制备核苷酸原液
  • 作为胞外核苷酸酶(ENT酶)抑制剂探测皮层神经元中的5′-ENT酶活性
  • 在体外研究中评估其对小猪小肠内主导菌株的生长影响

Biochem/physiol Actions

胞苷5′-单磷酸(CMP)可作为尿苷单磷酸(UMP)/胞苷单磷酸(CMP)激酶(酶代码 EC 2.7.4.4)的底物形成CDP,再磷酸化形成CTP,可支持DNA和RNA的生物合成。
胞苷单磷酸(CMP)是糖类的核苷酸载体。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Charuni A Amarasekara et al.
Journal of chromatography. A, 1638, 461892-461892 (2021-01-22)
With advances in the design and fabrication of nanofluidic devices during the last decade, there have been a few reports on nucleic acid analysis using nanoscale electrophoresis. The attractive nature of nanofluidics is the unique phenomena associated with this length
Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration
Vaur P, et al.
Faseb Journal (2017)
Carbohydrate Metabolism III: Glycoproteins, Glycolipids, GPI Anchors, Proteoglycans, and Peptidoglycans
Medical Biochemistry, 307-330 (2002)
Anaerobic growth of Bacillus mojavensis and Bacillus subtilis requires deoxyribonucleosides or DNA
Folmsbee MJ, et al.
Applied and Environmental Microbiology, 70(9) (2004)
Balvinder Dhaliwal et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 62(Pt 8), 710-715 (2006-08-02)
The crystal structure of Staphylococcus aureus cytidine monophosphate kinase (CMK) in complex with cytidine 5'-monophosphate (CMP) has been determined at 2.3 angstroms resolution. The active site reveals novel features when compared with two orthologues of known structure. Compared with the

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