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Merck
CN

C0856

Sigma-Aldrich

C7BzO

别名:

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

经验公式(希尔记法):
C21H37NO4S
分子量:
399.59
MDL编号:
UNSPSC代码:
12161902
PubChem化学物质编号:
NACRES:
NA.56

描述

zwitterionic

质量水平

方案

≥95.0% (HPLC)

表单

solid

分子量

399.59 Da (anhydrous)

聚集数

≤25

技术

dialysis: suitable
electrophoresis: suitable
protein quantification: suitable

SMILES字符串

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

一般描述

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.

应用

C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.

其他说明

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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T Rabilloud et al.
Electrophoresis, 20(18), 3603-3610 (1999-12-28)
Parasite-encoded membrane proteins translocated to the surface of infected erythrocytes or in specialized vesicles underneath (Maurer's clefts) play a key role in the asexual life cycle of Plasmodium falciparum (a malaria-causing protozoan), by mediating key steps such as red blood
Structure-efficiency relationships of zwitterionic detergents as protein solubilizers in two-dimensional electrophoresis
Tastet C, et al.
Proteomics, 3(2), 111-121 (2003)
Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions
Rehbein P and Schwalbe H
Protein Expression and Purification, 150, 53-60 (2018)
Proteomic response of the biological control fungus Trichoderma atroviride to growth on the cell walls of Rhizoctonia solani
Grinyer J, et al.
Current Genetics, 47(6), 381-388 (2005)
Hari B Krishnan et al.
Proteomics, 9(11), 3174-3188 (2009-06-16)
2-D analysis of plant proteomes containing thousands of proteins has limited dynamic resolution because only abundant proteins can be detected. Proteomic assessment of the non-abundant proteins within seeds is difficult when 60-80% is storage proteins. Resolution can be improved through

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