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Merck
CN

C0780

Sigma-Aldrich

一水肌酸

suitable for cell culture

别名:

N-胺肉胺酸, α-甲胍乙酸

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About This Item

线性分子式:
H2NC(=NH)N(CH3)CH2CO2H
CAS号:
分子量:
131.13
Beilstein:
907175
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26

产品名称

一水肌酸, anhydrous

等级

anhydrous

质量水平

表单

powder

技术

cell culture | mammalian: suitable

颜色

white

SMILES字符串

CN(CC(O)=O)C(N)=N

InChI

1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)

InChI key

CVSVTCORWBXHQV-UHFFFAOYSA-N

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应用

肌酸(Cr)和磷酸肌酸(PCr)通过肌酸激酶的作用主要在骨骼肌组织中快速产生ATP。肌酸可用作研究其摄取机制和作用代谢的补充剂。

生化/生理作用

肌酸是一种含氮化合物,可充当 ATP 快速再生的高能量储存库。
肌酸是一种含氮化合物,可充当 ATP 快速再生的高能量储存库。大约 95% 的肌酸存在于骨骼肌中,主要为磷酸肌酸。肌酸可通过饮食摄入,也可由 L-精氨酸、甘氨酸和 L-蛋氨酸在肾脏和肝脏发生的多步骤反应中形成。肌酸随后被转运至肌肉组织。肌酸补充剂主要通过增加肌肉质量来增强运动成绩。肌酸还被研究用于神经肌肉疾病的治疗,可能有助于神经保护和改善细胞生物能量状态。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Philippe Généreux et al.
Journal of the American College of Cardiology, 65(6), 533-543 (2015-02-14)
Bifurcation lesions are frequent among patients with symptomatic coronary disease treated by percutaneous coronary intervention. Current evidence recommends a conservative (provisional) approach when treating the side branch (SB). The TRYTON (Prospective, Single Blind, Randomized Controlled Study to Evaluate the Safety
Subrata Patra et al.
Amino acids, 42(6), 2319-2330 (2011-07-20)
The creatine/creatine kinase (CK) system plays a key role in cellular energy buffering and transport. In vertebrates, CK has four isoforms expressed in a tissue-specific manner. In the process of creatine biosynthesis several other important metabolites are formed. The anticancer
Gregg W Stone et al.
JACC. Cardiovascular interventions, 8(7), 927-936 (2015-05-25)
This study sought to determine whether pre-percutaneous coronary intervention (PCI) plaque characterization using near-infrared spectroscopy identifies lipid-rich plaques at risk of periprocedural myonecrosis and whether these events may be prevented by the use of a distal protection filter during PCI.
Theo Wallimann et al.
Amino acids, 40(5), 1271-1296 (2011-03-31)
The pleiotropic effects of creatine (Cr) are based mostly on the functions of the enzyme creatine kinase (CK) and its high-energy product phosphocreatine (PCr). Multidisciplinary studies have established molecular, cellular, organ and somatic functions of the CK/PCr system, in particular
Dan Atar et al.
European heart journal, 36(2), 112-119 (2014-09-03)
The MITOCARE study evaluated the efficacy and safety of TRO40303 for the reduction of reperfusion injury in patients undergoing revascularization for ST-elevation myocardial infarction (STEMI). Patients presenting with STEMI within 6 h of the onset of pain randomly received TRO40303

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