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About This Item
经验公式（希尔记法）:
C5H10N2O3S
CAS号:
分子量:
178.21
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
推荐产品
产品名称
半胱氨酸-甘氨酸, ≥85% (TLC)
质量水平
方案
≥85% (TLC)
表单
solid
技术
HPLC: suitable
储存温度
−20°C
SMILES字符串
NC(CS)C(=O)NCC(O)=O
InChI
1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)
InChI key
ZUKPVRWZDMRIEO-UHFFFAOYSA-N
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一般描述
半胱氨酰甘氨酸是一种二肽，为谷胱甘肽分解代谢的副产物。
应用
半胱氨酰甘氨酸用于对羟基汞苯甲酸（PHMB）的衍生化，用紫外可见二极管阵列检测器（RPLC-DAD）进行在线和连续的反相色谱校准。
生化/生理作用
L-半胱氨酸-L-甘氨酸 (Cys-Gly) 用于谷胱甘肽的稳态研究。Cys-Gly 是巯基稳态、氧化应激和金属管理领域研究的重要分子。
半胱氨酰甘氨酸是神经元中谷胱甘肽生物合成的前体。在过渡金属离子存在的条件下，有利于产生活性氧物质。正常的半胱氨酰甘氨酸水平对于维持正常细胞功能至关重要。
其他说明
谷胱甘肽片段
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Werner Siems et al.
Archives of biochemistry and biophysics, 503(2), 248-252 (2010-09-02)
Intracellular metabolism of 4-hydroxy-2-nonenal (HNE), a major product and mediator of oxidative stress and inflammation, is analyzed in resting and fMLP-stimulated human polymorphonuclear leukocytes (PMNL), where this compound is generated during activation of the respiratory burst. HNE consumption rate in
Rafał Głowacki et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(28), 3400-3404 (2009-06-30)
A fully automated HPLC method for the simultaneous determination of total thiols in plasma samples has been developed. The method involves reductive conversion of disulfides to their reduced counterparts with the use of tris(2-carboxyethyl)phosphine. After reduction the newly formed sulfhydryl
Sara Trevisan et al.
Physiologia plantarum, 166(3), 794-811 (2018-09-22)
Nitrogen (N) is an indispensable nutrient for crops but its availability in agricultural soils is subject to considerable fluctuation. Plants have developed plastic responses to external N fluctuations in order to optimise their development. The coordinated action of nitric oxide
Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione
Dringen R, et al.
The Journal of Neuroscience, 19(2), 562-569 (1999)
Sandra Osburn et al.
Journal of the American Society for Mass Spectrometry, 23(6), 1019-1023 (2012-03-01)
The radical cations of Cys-Gly and Gly-Cys were studied using ion-molecule reactions (IMR), infrared multiple-photon dissociation (IRMPD) spectroscopy, and density functional theory (DFT) calculations. Homolytic cleavage of the S-NO bond of nitrosylated precursors generated radical cations with the radical site
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