C0158
L -肉碱 内盐
≥98%
别名:
左旋肉毒碱, 维生素 BT
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
(CH3)3N+CH2CH(OH)CH2COO-
化学文摘社编号:
分子量:
161.20
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
208-768-0
MDL number:
Beilstein/REAXYS Number:
4292315
产品名称
L -肉碱 内盐, synthetic, ≥98%
assay
≥98%
form
powder
color
white
InChI key
PHIQHXFUZVPYII-ZCFIWIBFSA-N
InChI
1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
SMILES string
C[N+](C)(C)C[C@H](O)CC([O-])=O
biological source
synthetic
mp
197-212 °C (lit.)
application(s)
cell analysis
detection
Quality Level
正在寻找类似产品? 访问 产品对比指南
Application
L-肉碱内盐已被用作Seahorse XF线粒体应激测定中的测定培养基的组分。它还被口服给予荷瘤小鼠，以研究其对过氧化物酶体增殖物激活受体的调节作用，从而对肝脏炎症反应进行分析。
Biochem/physiol Actions
肉毒碱是一种天然存在于大多数哺乳动物组织中的季铵。它在骨骼肌和心脏中参与能量代谢调控，浓度相对较高。它可将葡萄糖代谢由糖酵解转移至糖原储存，并促进长链脂肪酸向线粒体转运，使其在线粒体氧化产生能量。
肉碱由赖氨酸生物合成。肉碱可促进脂肪酸转运至线粒体区室中。在骨骼肌和心肌组织中，它充当代谢辅助因子。肉碱可能与支链氨基酸的能量产生有关。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles
Rui Li
The Journal of Physiology, 594(24), 7197-7213 (2016)
L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPAR? signaling
Fang Jiang
Molecular Medicine Reports, 13(2) (2015)
Sunil K Panchal et al.
Food & function, 6(8), 2496-2506 (2015-07-21)
Obesity and dyslipidaemia are metabolic defects resulting from impaired lipid metabolism. These impairments are associated with the development of cardiovascular disease and non-alcoholic fatty liver disease. Correcting the defects in lipid metabolism may attenuate obesity and dyslipidaemia, and reduce cardiovascular
Sandra Wächter et al.
Clinica chimica acta; international journal of clinical chemistry, 318(1-2), 51-61 (2002-03-07)
Long-term administration of high oral doses of L-carnitine on the skeletal muscle composition and the physical performance has not been studied in humans. Eight healthy male adults were treated with 2 x 2 g of L-carnitine per day for 3
Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects.
Ahmad S
Kidney International, 38(5), 912-918 (1990)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持